Habib Ghaznavi

Health Promotion Research Centre, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

[ 1 ] - A preliminary study of the association between the ABCA1 gene promoter DNA methylation and coronary artery disease risk

Coronary artery disease (CAD) is a common health problem in Iranian population. ATP binding cassette transporter A1 (ABCA1) plays central role in the efflux of the cholesterol from peripheral tissues back to liver. Inactivation of ABCA1 by epigenetic change such as DNA methylation may contribute to the development of CAD. The present study investigated the association between promoter DNA methy...

[ 2 ] - Association study between DNA methylation and genetic variation of APOE gene with the risk of coronary artery disease

Coronary artery disease (CAD) is a common health problem with a high rate of disability and death. Dyslipidemia and altered metabolism of Apo-lipoproteins are involved in the CAD pathogenesis. The current study investigated two common polymorphisms (rs429358 and rs7412) and promoter DNA methylation status of APOE in the Iranian CAD patients and control subjects. Two hundred angiographi...

نویسندگان همکار