Abbas Ahmadi

[ 1 ] - Synthesis and Determination of Chronic and Acute Thermal and Chemical Pain Activities of a New Derivative of Phencyclidine in Rats

Phencyclidine (1-(1-phenylcyclohexyl) piperidine, PCP, I) and ketamine (2-O-chlorophenyl-2-methylaminocyclohexan, II) have shown analgesic effects. Some of its derivatives were synthesized and their biological properties have been studied. In this study, a new derivative of PCP, (1-[1-(3-methoxyphenyl) (tetralyl)] piperidine, PCP-OCH3-tetralyl, III) was synthesized and the acute thermal pain ...

[ 2 ] - Synthesis and Study of Anti-convulsive Effect of 1-[1-(4-Methylphenyl) (Cyclohexyl)] 4-piperidinol as a New Derivative of Phencyclidine by PTZ- Induced Kindling Model in Male Mice

Background and Objective: Regarding the prevalence of epilepsy in human society and with respect to insufficiency of usual treatments, new strategies and methods for medical treatment of epileptic patients are necessary. As NMDA receptor antagonists are the most prominent anti-epileptic drugs, in the present study, we synthesized and investigated anti-epileptic effect of a new piperidine deriva...

[ 3 ] - Synthesis and study of anticonvulsant effect of 1-[1-(4-methoxyphenyl) (cyclohexyl)] 4-piperidinol as a new derivative of phencyclidine in PTZ-induced kindling model in male mice

Background and Objective: Epilepsy is a common disease in communities. Since there is no cure for it and current treatments are not effective for every patient, new method for medical treatment of epileptic patients is necessary. As NMDA receptors antagonists are the most prominent anti-epileptic drugs, in this study we synthesized and investigated anti-epileptic effect of a new piperidine deri...

[ 4 ] - Synthesis and Determination of Chronic and Acute Thermal and Chemical Pain Activities of a New Derivative of Phencyclidine in Rats

Phencyclidine (1-(1-phenylcyclohexyl) piperidine, PCP, I) and ketamine (2-O-chlorophenyl-2-methylaminocyclohexan, II) have shown analgesic effects. Some of its derivatives were synthesized and their biological properties have been studied. In this study, a new derivative of PCP, (1-[1-(3-methoxyphenyl) (tetralyl)] piperidine, PCP-OCH3-tetralyl, III) was synthesized and the acute thermal pain ...

[ 5 ] - Photodegradation of Insecticide Chlorpyrifos in Aqueous Solution under Simulated Solar Light Irradiation Conditions using Babolrood River Water

Chlorpyrifos is an organophosphate insecticide, used to control foliage and soil-borne insect pests on a variety of food and feed crops. In the natural environment, Chlorpyrifos can be degraded through several possible processes, including photodegradation, biodegradation, and hydrolysis. In the present work the photodegradation and environmental fate of Chlorpyrifos in aqueo...