Zahra Kiasalari
Department of Physiology and Neurophysiology Research Center, School of Medicine, Shahed University, Tehran, Iran . Herbal Medicine Research Center, Shahed University, Tehran, Iran.
[ 1 ] - Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice
Considering the high rate of epilepsy today, with respect to the insufficiency of the available therapies, new strategies and methods are recommended for medical treatment of epileptic patients. Therefore, the present study experimentally investigated the anticonvulsant effect of a herbal medicine candidate brassica nigra, by using kindling method. Sixty male mice were randomly selected and div...
[ 2 ] - Methadone and haloperidol combination effect on the acquisition and expression of morphine tolerance and dependence in male mice
Background and Objective: Today, opioids are used to control and relieve acute and chronic pain. However, the incidence of both tolerance and dependence phenomena for these drugs is a major problem. So, in this study, the combination effect of haloperidol and methadone on the acquisition and expression of morphine dependence and tolerance was examined. Materials and Methods: Ninety-eight mic...
[ 3 ] - Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice
Considering the high rate of epilepsy today, with respect to the insufficiency of the available therapies, new strategies and methods are recommended for medical treatment of epileptic patients. Therefore, the present study experimentally investigated the anticonvulsant effect of a herbal medicine candidate brassica nigra, by using kindling method. Sixty male mice were randomly selected and div...
[ 4 ] - ارزیابی اثر عصاره هیدروالکلی دانه بنگ‌دانه بر درد حاد و مزمن در موش صحرایی نر
سابقه و هدف: درد به عنوان شایع‌ترین شکایت بالینی و تجربه‌ای ناخوشایند بیماران را وادار به استفاده از ترکیبات مسکن می‌سازد. مطالعات اخیر نشان داده‌اند که ترکیبات آلکالوئیدی آنتی‌کولینرژیک دارای خاصیت ضددرد قوی هستند. با توجه به وجود ترکیبات آلکالوئیدی آنتی‌کولینرژیک در بنگ‌دانه و در نظر گرفتن اینکه در طب سنتی ایران اثر ضد دردی این گیاه ذکر شده است، هدف این مطالعه بررسی اثر ضد دردی مصرف خوراکی و ...
[ 5 ] - Protective effect of chlorogenic acid in an experimental model of Parkinson’s disease induced by 6-hydroxydopamine in rats
Introdution: Parkinson's disease is the second most common neurodegenerative disease. Considering the antioxidant and neuroprotective properties of chlorogenic acid, the purpose of this study was to evaluate the neuroprotective effect of this substance in an experimental model of Parkinson's disease. Methods: In this experimental study, Wisar male rats (n = 32) were divided into 4 groups: sham...
[ 6 ] - The effect of nobiletin on performance of rats in forced swimming and elevated plus maze tests in intranigral lipopolysaccharide rat model of Parkinson's disease
Background and Objective: Anti-inflammatory property of nobiletin (NOB) is proven and neuroinflammation is involved in triggering and progression of neurodegenerative disorder such as Parkinson's disease (PD). PD is a neurodegenerative disorder characterized by motor and non-motor features including psychiatric symptoms such as depression and anxiety. The purpose of this study to investigate wh...
نویسندگان همکار