Mehran Kouchek

[ 1 ] - Carbapenem restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital

Development of antibiotic resistance in Intensive Care Units (ICUs) is a worldwide problem. The purpose of this study was to evaluate the effect of an antibiotic stewardship program (ASP) by carbapenems restriction on gram-negative antimicrobial resistance in ICU. The study was designed in a 21 bedded general ICU of a teaching hospital with two wings (one and two) in Tehran, Iran. Carbapenem pr...

[ 2 ] - A Comparative Study of Intravenous Paracetamol and Fentanyl for Pain Management in ICU

Pain in ICU patients should be managed effectively and safely. Fentanyl and Paracetamol are used frequently in ICU. However experience using IV Paracetamol in the setting of critically ill patients is limited. We evaluated the analgesic effect and adverse reactions of intravenous Paracetamol compared to Fentanyl in ICU patients with mild to moderate pain. Forty patients in a general ICU were ra...

[ 3 ] - Potential Drug-drug Interactions in Post-CCU of a Teaching Hospital

Drug-drug interactions (DDIs) can lead to increased toxicity or reduction in therapeutic efficacy. This study was designed to assess the incidence of potential drug interactions (PDI) and rank their clinical value in post coronary care unit (Post-CCU) of a teaching hospital in Tehran, Iran.In this prospective study, three pharmacists with supervision of a clinical pharmacist actively gathered n...

[ 4 ] - Carbapenem restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital

Development of antibiotic resistance in Intensive Care Units (ICUs) is a worldwide problem. The purpose of this study was to evaluate the effect of an antibiotic stewardship program (ASP) by carbapenems restriction on gram-negative antimicrobial resistance in ICU. The study was designed in a 21 bedded general ICU of a teaching hospital with two wings (one and two) in Tehran, Iran. Carbapenem pr...

[ 5 ] - A Comparative Study of Intravenous Paracetamol and Fentanyl for Pain Management in ICU

Pain in ICU patients should be managed effectively and safely. Fentanyl and Paracetamol are used frequently in ICU. However experience using IV Paracetamol in the setting of critically ill patients is limited. We evaluated the analgesic effect and adverse reactions of intravenous Paracetamol compared to Fentanyl in ICU patients with mild to moderate pain. Forty patients in a general ICU were ra...

[ 6 ] - Potential Drug-drug Interactions in Post-CCU of a Teaching Hospital

Drug-drug interactions (DDIs) can lead to increased toxicity or reduction in therapeutic efficacy. This study was designed to assess the incidence of potential drug interactions (PDI) and rank their clinical value in post coronary care unit (Post-CCU) of a teaching hospital in Tehran, Iran.In this prospective study, three pharmacists with supervision of a clinical pharmacist actively gathered n...

[ 7 ] - بررسی میزان بروز DIC-like syndrome و تاثیر آن بر مورتالیتی و روزهای بستری در بیماران بخش مراقبت های ویژه بیمارستان امام حسین (ع) در سال های 92-96

زمینه و هدف: انعقاد درون رگی منتشر (DIC)، فعال‌شدن پاتولوژیک سیستم انعقاد خون به‌ صورت منتشر در رگ‌های مختلف بدن است، که از شایع ترین اختلالات پاراکلینیکی در بیماران بستری در بخش مراقبت های ویژه (ICU) می باشد. در مطالعه حاضر، میزان بروز سندرم شبه DIC و تاثیر آن بر میزان مورتالیتی و روزهای بستری در بیماران بخش مراقبت های ویژه ارزیابی شد. روش‌ها: مطالعه حاضر به روش کوهورت تاریخی بین سالهای 92 تا ...

[ 8 ] - Effect of High-Dose Vitamin D on Duration of Mechanical Ventilation in ICU Patients

The relationship of vitamin D3 with the duration of mechanical ventilation and mortality is still unknown. Therefore, this study aimed to determine the effect of using high-dose vitamin D on the duration of mechanical ventilation among the patients admitted to the intensive care unit. The current double-blinded clinical trial was performed on 44 mechanically ventilated, adult patients. Us...

[ 9 ] - Effect of High-Dose Vitamin D on Duration of Mechanical Ventilation in ICU Patients

The relationship of vitamin D3 with the duration of mechanical ventilation and mortality is still unknown. Therefore, this study aimed to determine the effect of using high-dose vitamin D on the duration of mechanical ventilation among the patients admitted to the intensive care unit. The current double-blinded clinical trial was performed on 44 mechanically ventilated, adult patients. Us...

[ 10 ] - Impact of a High-protein Nutritional Intake on the Clinical Outcome of the Neurocritical Patients

Disease-related malnutrition of neurocritical illness harms its treatment, which increases the mortality rate. The aim of this study was evaluating the effect of a high protein diet on the dietary factors, clinical outcome, and mortality rate of neurocritical patients. In a randomized controlled trial, 15 neurocritical patients were recruited in each group. Patients in the intervention and cont...

[ 11 ] - Impact of a High-protein Nutritional Intake on the Clinical Outcome of the Neurocritical Patients

Disease-related malnutrition of neurocritical illness harms its treatment, which increases the mortality rate. The aim of this study was evaluating the effect of a high protein diet on the dietary factors, clinical outcome, and mortality rate of neurocritical patients. In a randomized controlled trial, 15 neurocritical patients were recruited in each group. Patients in the intervention and cont...