Ali Nikseresht

[ 1 ] - Inhibition of NR2B-Containing N-methyl-D-Aspartate Receptors (NMDARs) in Experimental Autoimmune Encephalomyelitis, a Model of Multiple Sclerosis

Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been suggested for neuroprotection, but selective antagonisation of the NR2B subtype of these receptors, a subtype believed to play a more pivotal ...

[ 2 ] - Inhibition of NR2B-Containing N-methyl-D-Aspartate Receptors (NMDARs) in Experimental Autoimmune Encephalomyelitis, a Model of Multiple Sclerosis

Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been suggested for neuroprotection, but selective antagonisation of the NR2B subtype of these receptors, a subtype believed to play a more pivotal ...

[ 3 ] - Association Between MTHFR Genetic Variants and Multiple Sclerosis in a Southern Iranian Population

Multiple sclerosis (MS) is a demyelinating neuro- inflammatory autoimmune disease of the central nervous system. Genetic predisposition has long been suspected in the etiology of this disease. The association between MTHFR polymorphisms and MS has been ivestigated in different ethnic groups. We investigated the association between MTHFR C677T and A1298C missense variants and MS in 180 patients ...

[ 4 ] - Prevalence and Incidence of Multiple Sclerosis in Fars Province, Southern Iran

Background: Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system, which is accompanied by significant disabilities. Although there are some published data regarding the epidemiological features of MS in other parts of Iran, scarce data are available about the prevalence and demographic characteristics of MS in Fars province. The current study...

[ 5 ] - The Effects of Lamotrigine on Pain, Sleep, and Mood in Refractory Form of Central Post-Stroke Pain Syndrome

Background: Central post-stroke pain (CPSP) is a distressing pain syndrome, sometimes become refractory to the conventional pain managements. Anticonvulsants have been used to alleviate different central pains. Lamotrigine is a novel anticonvulsant and its proper dosage and its efficacy have not been well studied yet. The aim of this study was to evaluate the effect of 100 mg lamotrigine on ref...

[ 6 ] - A one-day visit of the EEG and EMG/NCV departments during neurology course for medical students of Shiraz University of Medical Sciences

Dear editor Today, an important part of the patients’diagnostic activities includes paraclinicaltests and procedures, which follow theircompleted history-taking and clinicalexaminations, in such a way that many medicalscience sources in different fields considerthem to be follow-up activities of clinicalexaminations. This is also the case in the field ofneurology and many of its specialized sub...