reza Alizadeh Navaei

[ 1 ] - Determination of antibiotics consumption in Buali_Sina Pediatric Hospital, Sari 2010-2011

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

[ 2 ] - Determination of antibiotics consumption in Buali_Sina Pediatric Hospital, Sari 2010-2011

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

[ 3 ] - تولیدات علمی ایران در حوزه سرطان شناسی بر اساس پایگاه های استنادی

Background and purpose: The status and role of each country in scientific production in specific fields may indicate the potential and its performance in promoting and improving that particular issue. Cancer is a major health problem in Iran, so this study aimed to investigate the role of scientific production of Iran about cancer. Materials and methods: We conducted a scientometric study us...

[ 4 ] - Serum mannan-binding lectin in patients with pulmonary tuberculosis: Its lack of a relationship to the disease and response to treatment

Background: Lectin pathway mediates complement activation, which is activated by many microorganisms. This study aimed at determining the serum levels of mannose-binding lectin (MBL) in patients with pulmonary tuberculosis, assessing its relationship to antiuberculosis treatment response, and comparing them with a control group.    Methods: This cross-sectional study was conducted on...

[ 5 ] - تاثیر ترومبولیز پیش بیمارستانی بر روی مورتالیتی بیماران مبتلا به انفارکتوس قلبی: یک مطالعه مرور سیستماتیک و متاآنالیز

Background and purpose: Early treatment of thrombolysis can reduce mortality in patients with myocardial infarction, so, this systematic review and meta-analysis aimed to compare the effect of pre-hospital thrombolysis and in-hospital thrombolysis on short-term mortality in patients with myocardial infarction. Materials and methods: Systematic search was conducted in electronic databases inclu...

[ 6 ] - Human papillomavirus and gastrointestinal cancer in Iranian population: A systematic review and meta-analysis

Background: Gastrointestinal (GI) malignancies are the most common cancers and account for nearly half of all cancer-related deaths in Iran. There was a strong association between human papillomavirus (HPV) infection and urogenital cancers, in particular the cervix. However, there is no clear causal relationship in all types of cancers, including gastrointestinal cancers. Therefore, the present...

[ 7 ] - Comparison of early and late intravenous gamma globulin treatment of Kawasaki disease on fever and cardiovascular complications

Background: Cardiac involvement was the major leading cause of death in patients with Kawasaki and IVIG administration reduces cardiac complications. The objective of this study was to determine the frequency of cardiovascular complications and duration of fever with regard to the time of intravenous immunoglobulin (IVIG) administration of patients with Kawasaki disease. Methods: This follow...

[ 8 ] - Evaluation the helicobacter pylori infection in asthmatic children compared to control group

Background: Asthma is a highly prevalent chronic respiratory disease in children. Moreover, the underlying causes of asthma exacerbation are important because they are effective in controlling and preventing asthma. The aim of this study was to evaluate the helicobacter pylori infection in controlled and uncontrolled asthmatic children compared to healthy children. Methods: This case- contro...

[ 9 ] - تاثیر بکلومتازون استنشاقی با و بدون مونته لوکاست خوارکی در کنترل آسم پایدار کودکان

سابقه و هدف: کورتیکواستروئید استنشاقی خط اول درمان در بیماری آسم می باشد که عوارضی را نیز به مراه خود دارد. در عوض مونته لوکاست عارضه کمتری داشته و به دلیل فرم دارو که بصورت قرص می باشد استفاده از آن نیز راحتتر می باشد. لذا این مطالعه با هدف مقایسه تاثیر بکلومتازون استنشاقی با و بدون مونته لوکاست خوارکی در کنترل آسم پایدار کودکان انجام شد. مواد و روش­ها: این مطالعه کارآزمایی بالینی بر روی 84 کو...

[ 10 ] - ارزیابی تراکم استخوان در کودکان 6 تا 14 ساله مبتلا به آسم تحت درمان با فلوتیکازون

سابقه و هدف: کورتیکواستروئید یکی از درمان های اصلی در آسم بوده و با توجه به اثراتی که کورتون ها بر تراکم معدنی استخوان دارند این مطالعه با هدف بررسی تراکم معدنی استخوان در کودکان مبتلا به آسم، تحت درمان با کورتون استنشاقی انجام شد. مواد و روش­ها: این مطالعه مقطعی بر روی 62 کودک 6 تا 14ساله مبتلا به آسم متوسط یا شدید مراجعه کننده به بیمارستان کودکان امیرکلا که حداقل یک سال از مدت بیماری گذشته و ...

[ 11 ] - ارتباط پلی مورفیسم C3435T ژن MDR1 با پاسخ به درمان در بیماران سرطان پستان

Background and purpose: Breast cancer is the most common cancer in women. Most recently C3435T polymorphism of MDR1 gene is considered as one of the major causes of drug resistance in treatment of this disease. This study was conducted to investigate the relationship between C3435T MDR1 gene polymorphism and treatment response in breast cancer patients. Materials and methods: In this longitudi...

[ 12 ] - Association between Anthropometric Indices and Breast Cancer Based on the Data of the Enrolment Phase (cross-sectional) in Tabari Cohort Study: The Causal Relationship or Violation of Temporality

Background and purpose: The relationship between obesity and the risk of breast cancer has been highlighted in some studies. This research aimed at studying the association between anthropometric indices and breast cancer based on enrolment phase (cross-sectional phase) data in Tabari cohort study. Materials and methods: In this cohort, 51 cases of breast cancer were recorded which were consid...

[ 13 ] - Normal values of neutrophils/lymphocytes ratio, lymphocytes/monocytes ratio and platelets/lymphocytes ratio among Iranian population: Results of Tabari cohort

Background: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population. Methods: In the present study, cross-sectiona...

[ 14 ] - Association between pre-chemotherapy serum levels of vitamin D and clinicopathologic findings in gastric cancer

Background: To examine serum levels of vitamin D in newly diagnosed gastric cancer (GC) patients compared with normal subjects and any possible association with prognostic variables. Methods: One-hundred subjects (50 GC and 50 controls) were enrolled and serum vitamin D levels were assessed using ELISA. Based on two definitions, vitamin D was classified as a sufficient level (≥30 ng/dL) and op...

[ 15 ] - Motivation and Barriers to Research Activities in Clinical Professors in Mazandaran University of Medical Sciences, 2019

Background and purpose: Research is one of the significant foundations of community development, which requires understanding the capabilities, weaknesses and strengths of programs. This study aimed at investigating the motivations and barri ers to research in clinical faculty members. Materials and methods: This descriptive-analytical study was conducted in clinical faculty members (surgeon a...

[ 16 ] - Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in COVID-19 Patients and Control Group and Relationship with Disease Prognosis

Background: The present study aimed to compare the complete blood count (CBC) indices between COVID-19 patients and the control group, and assess the relationship of these indices with COVID-19 prognosis given the role of complete blood counts in the COVID-19 prognosis. Methods: COVID-19 patients (confirmed by PCR or CT-Scan) who visited Imam Hospital in Sari were selected in this case-control...

[ 17 ] - Effect of a Herbal Medicine Containing Satureja hortensis L., Hypericum perforatum L. and Foeniculum vulgare L. on Patients with COVID-19 Infection

 Background and purpose: This research aimed at investigating the effect of herbal medicine on reduction of pulmonary complications in patients with Coronavirus disease 2019 (COVID-19). Materials and methods: Forty patients with COVID-19 infection older than 18 years of age (60% men) with the average age of over 55 years old enrolled in this study. Written consent was obtained and participants...

[ 18 ] - Serum, hair and nail Zinc level in children with asthma; zinc supplemental treatment in children with asthma: a systematic and meta-analysis review article

[ 19 ] - Role of Frizzled receptor expression on patients’ survival with gastrointestinal cancers: A systematic review with meta-analysis

Background: Frizzled receptors (FZD) play a pivotal role in the initiation and progression of a wide array of cancers. Dysregulated expression of FZD receptors is correlated with higher metastasis and invasive potential, as well as short survival in many malignancies. In this meta-analysis, we aimed to verify the prognostic value of FZD receptor expression on patients’ survival with different t...

[ 20 ] - Estimating the Relationship between Serum Electrolytes and COVID-19: A systematic Review and Meta-Analysis

Background and purpose: There are controversies on the association between electrolytes and Coronavirus disease 2019 (COVID-19) and its severity. Studies on these issues may help in resolving ambiguities. The purpose of this study was to assess the association between electrolyte indices and being infected with COVID-19 and developing severe symptoms using a meta-analysis. Materials and method...

[ 21 ] - Clinical Epidemiology of Deceased COVID-19 Patients in Mazandaran Heart Center, 2020-2021

Background and purpose: Clinical epidemiology of deceased COVID-19 patients is of great importance in identifying the risk factors for mortality and controlling the pandemic. In this study, we studied the demographic and clinical characteristics of deceased COVID-19 patients in Sari Fatemeh Zahra Hospital, Iran, between March 2020 and February 2021. Materials and methods: This retrospective cr...

[ 22 ] - Association of Diabetes and Metformin Use with Gastric Cancer: A Case-Control Study

 Background and purpose: Recently, several studies have shown type 2 diabetes to be associated with gastric cancer and metformin appears to inhibit the growth of cancer cells by inducing apoptosis. This study was conducted to investigate the relationship between metformin and gastric cancer. Materials and methods: This case-control study included patients with gastric cancer (case group, n= 12...

[ 23 ] - Frequency of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients in Sari Imam Khomeini Hospital

 Background and purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating condition that may require reduction or discontinuation of chemotherapy. Identifying effective methods in treatment of established CIPN requires determining the frequency of CIPN. There is a lack of comprehensive studies on this issue, so, this study was conducted to investigate the frequency of periphe...