Hossein Heli

[ 1 ] - Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite

Investigation of the redox properties of drugs and their determination are performed by electrochemical techniques. Data obtained from electrochemical techniques are often correlated with molecular structure and pharmacological activity of drugs. In this regard, different modified electrodes were applied as sensors for quantification of different drugs.A nanocomposite of reduced graphene oxide-...

[ 2 ] - Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite

Investigation of the redox properties of drugs and their determination are performed by electrochemical techniques. Data obtained from electrochemical techniques are often correlated with molecular structure and pharmacological activity of drugs. In this regard, different modified electrodes were applied as sensors for quantification of different drugs.A nanocomposite of reduced graphene oxide-...

[ 3 ] - توسعه زیست‌حسگر آمپرومتری بدون آنزیم برای تعیین مقدار سیستئین و استیل سیستئین

سابقه و هدف: در سال‌های اخیر تحقیقات گسترده‌ای در زمینه خواص جالب نانوذرات و کاربرد آنها در طراحی زیست حسگرها انجام شده است. در این بین، توسعه زیست حسگرهایی که به سادگی ساخته شده و برای تعیین ترکیبات سولفیدریلی قابل اطمینان باشند، از اهمیت ویژه‌ای برخوردار است. در این تحقیق، یک زیست حسگر بدون آنزیم برای تشخیص سیستئین و N-استیل-L-سیستئین طراحی شد. روش بررسی: نانوذرات با هسته اکسید آهن و پوسته ...

[ 4 ] - سمیت نانومواد- تأثیر خواص فیزیکوشیمیایی

Nanomaterials involve the structures with at least one dimension of <100 nm. Recently, development in nanotechnology has led to the use of nanomaterials in many different fields. On the other hand, increasing use of nanomaterials has resulted in release of these materials to the environment. Therefore, before employing these materials in biological and living systems, they should be evaluated ...

[ 5 ] - مطالعه الکتروشیمیایی فرایندهای انتقال بار و جرم در نانوپوسته های کبالت اکسید

در این مقاله یک روش ساده و مؤثر برای ساخت نانوپوسته‌ های کبالت اکسید (II) ارایه می‌شود. مورفولوژی و ساختار شیمیایی نانوپوسته‌ ها با روش‌های گوناگون شامل میکروسکپ ‌های الکترونی (روبشی و عبوری)، پراش اشعه ایکس، میکروسکپی روبشی تونلی و روش‌های الکتروشیمیایی بررسی شد. مطالعه جامعی بر رفتار الکتروشیمیایی نانوپوسته‌ ها در فصل مشترک با الکترولیت، فرایندهای انتقال بار و ج...

[ 6 ] - Biosynthesis of Silver Nanoparticles Using Pine Pollen and Evaluation of the Antifungal Efficiency

Background: Nanoparticles have been applied to medicine, hygiene, pharmacy and dentistry, and will bring significant advances in the prevention, diagnosis, drug delivery and treatment of disease. Green synthesis of metal nanoparticles has a very important role in nanobiotechnology, allowing production of non-toxic and eco-friendly particles.Objectives: Gr...

[ 7 ] - Introducing Self-Nanoemulsifying Drug Delivery System to Increase the Bioavailability of Oral Medications

Due to low cost, ease of administration, and lack need for trained personnel, the oral route is the most convenient and accessible way to design different medicines that could be simply consumed by patients. Regardless of the great benefits of this route, the main challenge in the bioavailability of oral medications is gastrointestinal instability. Nanotechnology is used to improve the solubili...

[ 8 ] - Effect of Magnetic Fluid Hyperthermia on Implanted Melanoma in Mouse Models

Background: Nowadays, magnetic nanoparticles (MNPs) have received much attention because of their enormous potentials in many fields such as magnetic fluid hyperthermia (MFH). The goal of hyperthermia is to increase the temperature of malignant cells to destroy them without any lethal effect on normal tissues. To investigate the effectiveness of cancer therapy by magnetic fluid hyperthermia, Fe...

[ 9 ] - An Aptamer-based Biosensor for Troponin I Detection in Diagnosis of Myocardial Infarction

Background: Acute myocardial infarction (MI) accounts for one third of deaths. Cardiac troponin I (TnI) is a reliable biomarker of cardiac muscle tissue injury and is employed in the early diagnosis of MI.Objectives: In this study, a molecular method is introduced to early diagnosis of MI by rapid detection of TnI.Materials and Methods: The detection method was based on electrochemical aptasens...

[ 10 ] - Study of Nanofibrils Formation of Fibroin Protein in Specific Thermal and Acidity Conditions

Background: Amyloid fibrils are insoluble arranged aggregates of proteins that are fibrillar in structure and related to many diseases (at least 20 types of illnesses) and also create many pathologic conditions. Therefore understanding the circumstance of fibril formation is very important.Objectives: This study aims to work on fibrillar structure formation of fibroin (as a model protein)...