Somayeh Esmaeili

[ 1 ] - Naghibione; A Novel Sesquiterpenoid with Antiplasmodial Effect from Dorema hyrcanum Koso-Pol. Root, a Plant Used in Traditional Medicine

Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in vitro (pLDH assay) and in vivo (Peters’ 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line MDBK (MTT test). The IC50 values for a chloroquine- sensitive (3D7) and a chl...

[ 2 ] - Antiplasmodial Activity and Cytotoxicity of Plants Used in Traditional Medicine of Iran for the Treatment of Fever

Malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. Because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. Traditional medicine is one of the important sources of new antiplasmodial drugs.In this study, twenty methanolic extracts from different parts of sixteen medicinal plants used i...

[ 3 ] - Naghibione; A Novel Sesquiterpenoid with Antiplasmodial Effect from Dorema hyrcanum Koso-Pol. Root, a Plant Used in Traditional Medicine

Some Dorema species are used in Persian traditional medicine. In the present study the total extract from the roots of Dorema hyrcanum Koso-Pol. was investigated for its in vitro (pLDH assay) and in vivo (Peters’ 4-days suppressive test) antiplasmodial effects and assessed for cytotoxicity against the normal cell line MDBK (MTT test). The IC50 values for a chloroquine- sensitive (3D7) and a chl...

[ 4 ] - Antiplasmodial Activity and Cytotoxicity of Plants Used in Traditional Medicine of Iran for the Treatment of Fever

Malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. Because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. Traditional medicine is one of the important sources of new antiplasmodial drugs.In this study, twenty methanolic extracts from different parts of sixteen medicinal plants used i...

[ 5 ] - The Cytotoxic Effects of Ferula Persica var. Persica and Ferula Hezarlalehzarica against HepG2, A549, HT29, MCF7 and MDBK Cell Lines

Cancers belong to a group of disorders which are very important for researchers. Because they have several types and cause mortality in human beings. Many investigations are performing in order to introduce cheaper drugs with lower side effects especially with natural sources. Ferula <span style="font-family: TimesNewRom...