Massoud Amanlou

[ 1 ] - Synthesis of Some Spiro Indeno[1,2-b]pyrido[2,3-d]Pyrimidine-5,3′- Indolines as New Urease Inhibitors

New series of spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines as new urease inhibitors were synthesized by the catalytic procedure in high yield and short reaction time. In this method, biacidic carbon was prepared as a novel heterogeneous acid and was subsequently used as an efficient catalyst in this synthesis. The inhibitory activities of synthesized compounds were tested against Ja...

[ 2 ] - Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines

Urease enzyme has a crucial role in the persistent habitation of Helicobacter pylori (H. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. Plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 ...

[ 3 ] - Screening of 20 Commonly Used Iranian Traditional Medicinal Plants Against Urease

Infection with Helicobacter pyloriis the most common cause of stomach and duodenal ulcers. About more than 80 % of people are infected with H. pylori in developing countries. H. pyloriuses urease enzyme product “ammonia” in order to neutralize and protect itself from the stomach acidic condition and urease enzyme activity has been shown to be essential to the colonization of H. pylori. Inhibito...

[ 4 ] - A Preliminary Investigation of the Jack-bean Urease Inhibition by Randomly Selected Traditional used Herbal Medicine

Helicobacter pylori :28 µg/mL). (H. pylori) infection leads to different clinical and pathological outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric neoplasia and even gastric cancer and its eradiation dependst upon multi-drug therapy. The most effective therapy is still unknown and prompts people to make great efforts to find better and more modern natural or ...

[ 5 ] - Association of Saliva Fluoride Level and Socioeconomic Factors with Dental Caries in 3-6 Years Old Children in Tehran-Iran

Previous studies have indicated that there may be a relationship between the salivary fluoride concentrations and dental caries while the emphasis was on dental caries in permanent teeth. The aim of this study was to assess the prevalence of dental caries and its predictors in 3-6 year-old children in Tehran, Iran. The other objective of this investigation was to clarify a relationship between ...

[ 6 ] - Synthesis of Some Spiro Indeno[1,2-b]pyrido[2,3-d]Pyrimidine-5,3′- Indolines as New Urease Inhibitors

New series of spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines as new urease inhibitors were synthesized by the catalytic procedure in high yield and short reaction time. In this method, biacidic carbon was prepared as a novel heterogeneous acid and was subsequently used as an efficient catalyst in this synthesis. The inhibitory activities of synthesized compounds were tested against Ja...

[ 7 ] - Urease Inhibitory Activities of some Commonly Consumed Herbal Medicines

Urease enzyme has a crucial role in the persistent habitation of Helicobacter pylori (H. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. Plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 ...

[ 8 ] - Screening of 20 Commonly Used Iranian Traditional Medicinal Plants Against Urease

Infection with Helicobacter pyloriis the most common cause of stomach and duodenal ulcers. About more than 80 % of people are infected with H. pylori in developing countries. H. pyloriuses urease enzyme product “ammonia” in order to neutralize and protect itself from the stomach acidic condition and urease enzyme activity has been shown to be essential to the colonization of H. pylori. Inhibito...

[ 9 ] - A Preliminary Investigation of the Jack-bean Urease Inhibition by Randomly Selected Traditional used Herbal Medicine

Helicobacter pylori :28 µg/mL). (H. pylori) infection leads to different clinical and pathological outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric neoplasia and even gastric cancer and its eradiation dependst upon multi-drug therapy. The most effective therapy is still unknown and prompts people to make great efforts to find better and more modern natural or ...

[ 10 ] - Association of Saliva Fluoride Level and Socioeconomic Factors with Dental Caries in 3-6 Years Old Children in Tehran-Iran

Previous studies have indicated that there may be a relationship between the salivary fluoride concentrations and dental caries while the emphasis was on dental caries in permanent teeth. The aim of this study was to assess the prevalence of dental caries and its predictors in 3-6 year-old children in Tehran, Iran. The other objective of this investigation was to clarify a relationship between ...

[ 11 ] - Development and Validation of a Rapid Derivative Spectrophotometric Method for Determination of Tropicamide in Eye Drops

Tropicamide is an antimuscarinic agent used as eye drops for refractive examinations. The aim of this study was to develop a simple and suitable analytical method for determination of tropicamide in eye drops in the presence of excipients. A zero-crossing third and fourth derivative spectrophotometric method was described for determination of tropicamide in eye drops. The measurements wer...

[ 12 ] - Spectrophotometric Determination of Tropicamide in Bulk and Pharmaceutical Formulations

A simple and sensitive extractive spectrophotometric method is described for determination of tropicamide. The method is based on the reaction of tropicamide and bromocresol green. The ion-paired colored complex was extracted with chloroform at pH 3. The extracted complex showed maximum absorbance at 423 nm. The complex was stable up to 2 days and obeyed Beer's law over the concentration r...