Ahamad Shahir-Sadr
Bioinformatics Research Center, Sabzevar University of Medical Sciences, School of Medicine, Sabzevar, Iran.
[ 1 ] - Developing a CoMSIA model for inhibition of COX-2 by resveratrol derivatives
Design of selective cyclooxygenase-2 (COX-2) inhibitors is still a challenging task because of active site similarities between COX isoenzymes. To help with this issue, we tried to generate a 3D-QSAR (3 dimensional quantitative structure activity relationship) model that might reflect the essential features of COX-2 active sites. Compounds in a series of resveratrol derivatives inhibitors with ...
[ 2 ] - Developing a CoMSIA model for inhibition of COX-2 by resveratrol derivatives
Design of selective cyclooxygenase-2 (COX-2) inhibitors is still a challenging task because of active site similarities between COX isoenzymes. To help with this issue, we tried to generate a 3D-QSAR (3 dimensional quantitative structure activity relationship) model that might reflect the essential features of COX-2 active sites. Compounds in a series of resveratrol derivatives inhibitors with ...
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