Farid dorkoosh

[ 1 ] - Estimating Capacity Utilization in Iranian Pharmaceutical Industry: Pharmaceutical Companies on the Stock Exchange, 2008-2012

This study aims to measure the production capacity and capacity utilization in pharmaceutical industry. The capacity utilization is the ratio of actual production level to the potential production level which shows the gap between real production and production capacity. Method: Through econometric methods, the short-run translog cost function is estimated with the cost share function of produ...

[ 2 ] - Pectin Film Coated Pellets for Colon-targeted Delivery of Budesonide: In-vitro/In-vivo Evaluation in Induced Ulcerative Colitis in Rat

The main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH of 1.2 (2 ...

[ 3 ] - Design and Characterization of Mesalamine Loaded Nanoparticles for Controlled Delivery System

Objective(s): Nanoparticles (NPs) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. The main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. Methods: In this study, me...

[ 4 ] - Pluronic based nano-delivery systems; Prospective warrior in war against cancer

Pluronic based nano-particulate systems are innovative platforms for delivery of anti-cancer agents. These systems due to their pharmacological properties and suitable physicochemical characteristics are great opportunity for development cancer therapeutics. This mini-review tries to provide a more detailed overview on the currently available pluronic based drug delivery systems. In the section...

[ 5 ] - Estimating Capacity Utilization in Iranian Pharmaceutical Industry: Pharmaceutical Companies on the Stock Exchange, 2008-2012

This study aims to measure the production capacity and capacity utilization in pharmaceutical industry. The capacity utilization is the ratio of actual production level to the potential production level which shows the gap between real production and production capacity. Method: Through econometric methods, the short-run translog cost function is estimated with the cost share function of produ...

[ 6 ] - Pectin Film Coated Pellets for Colon-targeted Delivery of Budesonide: In-vitro/In-vivo Evaluation in Induced Ulcerative Colitis in Rat

The main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH of 1.2 (2 ...

[ 7 ] - Optimization of RGD-modified Nano-liposomes Encapsulating Eptifibatide

Background: Eptifibatide (Integrilin) is an intravenous (IV) peptide drug that selectively inhibits ligand binding to the platelet GP IIb/IIIa receptor. It is an efficient peptide drug, however has a short half-life. Therefore, antithrombotic agents like eptifibatide are required to become improved with a protected and targeted delivery system such as using nano-liposomes to the site of thrombu...