Zahra Sahraei

[ 1 ] - Study of The Effects of N-Acetylcysteine on Oxidative Stress Status of Patients on Maintenance-Hemodialysis Undergoing Cadaveric Kidney Transplantation

N-acetylcysteine (NAC) is a potent antioxidant that acts through regenerating glutathione stores and scavenging oxygen-free radicals. This study assesses the short-term effects of NAC in cadaveric kidney transplant (KT) recipients. A double blind, randomized, placebo controlled trial was designed and patients were randomly assigned to receive either NAC or placebo. Glutathione peroxidase (GPX) ...

[ 2 ] - Effect of vitamin D supplementation on procalcitonin as prognostic biomarker in patients with ventilator associated pneumonia complicated with vitamin D deficiency

Ventilator-associated pneumonia (VAP) is a common and serious problem that develops after more than 48 hours of mechanical ventilation. Improving the activity of immune system with vitamin D, and its consequent impact on prognostic biomarkers of VAP was studied in the current study. A randomized double blind placebo controlled clinical trial was designed. A total of 46 patients with VAP, who w...

[ 3 ] - Nephrotoxicity of high and conventional dosing regimens of colistin: A randomized clinical trial

BACKGROUND: Nephrotoxicity has been a major long-standing concern about colistin. This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin. METHODS: A randomized open-labeled clinical trial on 40 patients with multi-drug resistant gram negative infections was designed. Patients were allocated into two equal-size groups receiving high and conventional dose...

[ 4 ] - Study of The Effects of N-Acetylcysteine on Oxidative Stress Status of Patients on Maintenance-Hemodialysis Undergoing Cadaveric Kidney Transplantation

N-acetylcysteine (NAC) is a potent antioxidant that acts through regenerating glutathione stores and scavenging oxygen-free radicals. This study assesses the short-term effects of NAC in cadaveric kidney transplant (KT) recipients. A double blind, randomized, placebo controlled trial was designed and patients were randomly assigned to receive either NAC or placebo. Glutathione peroxidase (GPX) ...

[ 5 ] - Effect of vitamin D supplementation on procalcitonin as prognostic biomarker in patients with ventilator associated pneumonia complicated with vitamin D deficiency

Ventilator-associated pneumonia (VAP) is a common and serious problem that develops after more than 48 hours of mechanical ventilation. Improving the activity of immune system with vitamin D, and its consequent impact on prognostic biomarkers of VAP was studied in the current study. A randomized double blind placebo controlled clinical trial was designed. A total of 46 patients with VAP, who w...

[ 6 ] - Nephrotoxicity of high and conventional dosing regimens of colistin: A randomized clinical trial

BACKGROUND: Nephrotoxicity has been a major long-standing concern about colistin. This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin. METHODS: A randomized open-labeled clinical trial on 40 patients with multi-drug resistant gram negative infections was designed. Patients were allocated into two equal-size groups receiving high and conventional dose...