javad baharara

[ 1 ] - Silver nanoparticles Synthesized coating with Leaves Zataria multiflora extract Induced Apoptosis in HeLa cells through p53 activation

Aims: The biosynthesis of nanoparticles is widely considered today. The aim of this investigation was the biosynthesis and coating of Ag.NPs with Zataria multiflora (Zm-Ag.NPs) leaf extract and assess its apoptosis promoting effects. Methods: The Zm-Ag.NPs was characterized by UV-visible and FTIR spectroscopy, TEM, EDS, DLS and measurement of zeta-potential. Apoptosis induction effects of Zm-A...

[ 2 ] - Evaluation of the cytotoxic effect of the Brittle Star (Ophiocomaerinaceus) dichloromethane extract and doxorubicin on EL4 cell line

Leukemia is a blood disease which is caused by the inhibition of differentiation and an increased proliferation rate. Nature has been known as a rich source of medically useful substances. High diversity of bioactive molecules extracted from marine invertebrates, makes them ideal candidates for cancer researches. The study has been done to investigate cytotoxic effects of dichloromethane brittl...

[ 3 ] - Silver nanoparticles Synthesized coating with Leaves Zataria multiflora extract Induced Apoptosis in HeLa cells through p53 activation

Aims: The biosynthesis of nanoparticles is widely considered today. The aim of this investigation was the biosynthesis and coating of Ag.NPs with Zataria multiflora (Zm-Ag.NPs) leaf extract and assess its apoptosis promoting effects. Methods: The Zm-Ag.NPs was characterized by UV-visible and FTIR spectroscopy, TEM, EDS, DLS and measurement of zeta-potential. Apoptosis induction effects of Zm-A...

[ 4 ] - Evaluation of the cytotoxic effect of the Brittle Star (Ophiocomaerinaceus) dichloromethane extract and doxorubicin on EL4 cell line

Leukemia is a blood disease which is caused by the inhibition of differentiation and an increased proliferation rate. Nature has been known as a rich source of medically useful substances. High diversity of bioactive molecules extracted from marine invertebrates, makes them ideal candidates for cancer researches. The study has been done to investigate cytotoxic effects of dichloromethane brittl...

[ 5 ] - اثر عصاره بیضه گوسفند در رشد فولیکو ل‌های مو و ترمیم زخم پوست موش صحرایی نر نژاد ویستار

Since administration of androgens has been considered appreciable in hair follicle growth and wound healing, therefore the main objective in this study is evaluation the effect of sheep testis extract on improvement and growth of hair follicle and regeneration of injured Wistar rat skin. In this experimental study, rats were randomly divided into 7 groups, control (negative control), sham (trea...

[ 6 ] - The effect of exosomes derived from human ovarian epithelial cancer cells on the secretion of AMH and Inhibin in granulosa cells

Exosomes are secreted by different types of cells and known as biological packages. Exosomes have significant role in intercellular communications and involved in the development and progression of various diseases such as cancer. Inhibin B and anti-mullerian hormone (AMH) are markers of granulosa cell tumors (GCT) and due to the role of exosomes in the progression of cancer, in this experiment...

[ 7 ] - The effect of cerebrospinal fluid-derived exosomes on neural differentiation of adipose mesenchymal stem cells in alginate hydrogel scaffold

Nowadays, researchers have made extensive efforts to find new treatments for nerve damage. Meanwhile, the role of exosomes in cell-cell communication is considered to be a new mechanism. Exosomes can act as suitable differentiating agents. The aim of this study was to investigate the differentiating effect of cerebrospinal fluid-derived exosomes on adipose mesenchymal stem cells in alginate hyd...

[ 8 ] - Anticancer effect of Artemisia extract and cisplatin on induction of apoptosis and inhibition of proliferation in A2780 human ovarian cancer

Cisplatin, as a chemotherapy drug, causes serious side effects in the advanced stages of the cancer. Recently, Artemisia has been considered for its bioactive compounds, anti-proliferative and anti-inflammatory effects. The aim of this study was to evaluate the anti-cancer and anti-metastatic effects of the methanolic extract of aerial organs of Artemisia and cisplatin, either alone or in combi...