Abbas Pardakhty

[ 1 ] - Phytoniosome: a Novel Drug Delivery for Myrtle Extract

Traditionally, Myrtus communis (myrtle) has been used for treatment of several kinds of disorders. However, there are some factors, namely, low solubility and permeability, which restrict use of myrtle extract (ME) in medical applications. Regarding these limitations, the aim of the present study was to develop a new niosomal formulation to enhance ME stability and permeability. Briefly, sever...

[ 2 ] - Effects of ultrasound on properties of ni-metal organic framework nanostructures

Objective(s): According to the unique properties of magnetic nanoparticles, Nickel Metal-Organic Frameworks (MOF) was synthesized successfully by ultrasound irradiation. Metal-organic frameworks (MOFs) are organic–inorganic hybrid extended networks that are constructed via covalent linkages between metal ions/metal clusters and organic ligands called a linker. Materials and Methods: The nanopar...

[ 3 ] - Nano-niosomes in drug, vaccine and gene delivery: a rapid overview

Niosomes, non-ionic surfactant vesicles (NSVs), are the hydrated lipids composed mainly of different classes of non-ionic surfactants, introduced in the seventies as a cosmetic vehicle. Nowadays, niosomes are used as important new drug delivery systems by many research groups and also they are effective immunoadjuvants which some commercial forms are available in the market. These vesicles rece...

[ 4 ] - Phytoniosome: a Novel Drug Delivery for Myrtle Extract

Traditionally, Myrtus communis (myrtle) has been used for treatment of several kinds of disorders. However, there are some factors, namely, low solubility and permeability, which restrict use of myrtle extract (ME) in medical applications. Regarding these limitations, the aim of the present study was to develop a new niosomal formulation to enhance ME stability and permeability. Briefly, sever...

[ 5 ] - Biosynthesis of Srco3 nanostructures with honey as a green capping agent and reductant: photodynamic therapy

Objective (s): SrCO3 nanoparticles could be used as new biomedical sources in magnetic resonance imaging as a promising noninvasive imaging modality for the preoperative staging of breast cancer and monitoring of tumor response to therapy. The present study aimed to synthesize SrCO3 nanostructures using microwave irradiation in the presence of honey as a green capping agent and reductant. Mater...

[ 6 ] - Fetishism Due to Methamphetamine (Glass) Abuse: A Case Report

Background: Fetishism is a type of paraphilia. The focus of sexual arousal in fetishism is oriented towards inanimate objects. Sexual arousal and craving are some of the reasons the youth resort to crystal (glass). Drug abuse may cause disorders in sexual function. Case Report: The patient was a 41 years old man. He married in age 22 years and experienced frequent intercourses with his wife fro...

[ 7 ] - The physicochemical and organoleptic evaluation of the nano/micro encapsulation of Omega-3 fatty acids in lipid vesicular systems

Objective(s): Omega-3 fatty acids play a key role in maintaining human health. The present study aimed to reduce the fishy smell and taste of omega-3 fatty acids through the encapsulation of lipid vesicles. Materials and Methods: Different non-ionic surfactants from the sorbitan ester family and egg lecithin with cholesterol were utilized to form micro-niosomal and liposomal formulations ...

[ 8 ] - Exosome-loaded Paclitaxel: Preparation and toxicity evaluation on two glioblastoma cell lines

Objective(s): Exosomes are endogenous nanovesicles act as intercellular communication tools which have been considered to utilize as drug delivery systems. As transporting therapeutic molecules into brain has obstacles, preparing exosomes which have the potential to pass through its barriers is great challenge. Methods: Exosomes isolated from cell culture media of U87 glioblastoma ...

[ 9 ] - Ethanolic Extract of Propolis from Kerman Area Triggers Apoptosis and Arrests Cell Cycle in Three Human Breast Cancer Cell Lines MDA-MB-231, SKBR and MCF-7

Background: Cancer is one of the major health problems worldwide and natural resources are being explored to develop anticancer drugs with fewer side effects. Iranian propolis contains components including flavonoids and polyphenols and has various medicinal properties. The aim of this study was to investigate the effect of Ethanolic Extract of Sirch Propolis (EESP) on three br...

[ 10 ] - Effects of Boswellia serrata on Improvement of Memory Impairment in Patients with Mild Cognitive Impairment: A Double-blind, Randomized, Placebo-controlled Study

Background: Mild cognitive impairment (MCI) is the stage between the expected cognitive decline of normal aging and the more serious decline of dementia. In the present study, the effect of Boswellia serrata (BS) on improvement of memory impairment in patients with MCI was investigated. Methods: In this single-center randomized double-blind placebo-controlled ...