Masood Saleem Mir
Division of Veterinary Pathology, F.V.Sc. & A.H, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Kashmir (J&K), India
[ 1 ] - Streptozotocin Induced Acute Clinical Effectsin Rabbits (Oryctolagus cuniculus)
Background & Objectives: Streptozotocin (STZ) is used for induction of Type-1 diabetes mellitus in animal models. Its beta-cytotoxic action results in sudden release of insulin leading to severe hypoglycaemia and even mortality. However, its sensitivity varies with species. Present investigation was aimed at studying STZ induced acute clinical effects in rabbits. Methods: Str...
[ 2 ] - Pre-diabetic Clinical Changes Induced by Low Doses of Alloxan-Streptozotocin Cocktail in Rabbits
Background & Objectives: Alloxan & streptozotocin are used for inducing diabetic models. Their combination has been used to reduce the individual chemical dosage and minimize the side effects. Present investigation was aimed at studying pre-diabetic clinical changes induced by low doses of Alloxan-STZ cocktail in rabbits. Methods: New Zealand White rabbits, 1-1.5 kg body weight, were administe...
[ 3 ] - Efficacy of Abroma augusta on Biochemical and Histomorphological Features of Alloxan-Induced Diabetic Rabbits
Background and Objectives: Medicinal plants are well documented for possessing antidiabetic or antihyperglycaemic potential. Abroma augusta seems to have the same effect in treating diabetes mellitus. The aim of the present experiment was to report the efficacy of the aqueous extract of the leaves of A. augusta on biochemical and histological abnormaliti...
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