Saeid Amanpour

[ 1 ] - Results of Acellular Dermis Matrix Graft Used for Tympanoplasty in Guinea Pig Model

Introduction: To describe the underlay tympanoplasty technique using an acellular dermal graft(AlloDerm) for tympanic membrane (TM) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using AlloDerm tissue harvested from the prepuce as a source of tissue for future grafting in human TM reconstruction. Materials and Methods: The prepuce was divided during c...

[ 2 ] - Investigating the Release of Methotrexate and 5-Fluorouracil Anticancer Drugs from Multi-Layered Nanofiber Structure of Polycaprolactone/Chitosan

In this study, seven-layer nanofiber structures consisting of polycaprolactone/ chitosan polymers loaded with methotrexate and 5-fluorouracil anti-cancer drugs, for controlled drug delivery, were produced and evaluated. For this purpose, the second, fourth and sixth layers were loaded with drug and placed between the drug-free layers. The surface morphology of drug-free and drug-loaded nanofibe...

[ 3 ] - Fraction Bioactivity Screening of Mulberry Leaf and Two Flavonoids in Combination with Cisplatin on Human Gastric Adenocarcinoma Cells

The successful therapy strategy of gastric cancer is defined as devastating of the cancerous cells without exposing systematic toxicity and undesirable side effects. One strategy to overcome cancer treatment related difficulties could be combination therapy with natural products with anticancer drugs to introduce effective antitumor effects in addition to reduction of undesirable side effects. ...

[ 4 ] - Fraction Bioactivity Screening of Mulberry Leaf and Two Flavonoids in Combination with Cisplatin on Human Gastric Adenocarcinoma Cells

The successful therapy strategy of gastric cancer is defined as devastating of the cancerous cells without exposing systematic toxicity and undesirable side effects. One strategy to overcome cancer treatment related difficulties could be combination therapy with natural products with anticancer drugs to introduce effective antitumor effects in addition to reduction of undesirable side effects. ...