Subramanyam Padma
Department of Nuclear Medicine & PET/CT, Amrita Institute of Medical Sciences & Research Centre, Cochin, Kerala, India
[ 1 ] - Aplastic anemia evolving to myelodysplastic syndrome and later to a lymphoproliferative malignancy in a treated case of carcinoma breast: A case report emphasizing the importance of PET-CT in cutaneous T cell lymphoma
Although aplastic anemia (AA) and myelodysplastic syndrome (MDS) are separate entities with different management, distinction between the two can be difficult on morphological basis due to hypocellularity of bone marrow. MDS is one of the serious complications of AA. Karyotyping is definitive in the diagnosis of MDS. Better and robust investigations like 18F-Fluoro-deoxy-Glucose Posi...
[ 2 ] - Tracing ischemic memory by metabolic pathways: BMIPP and beyond
Myocardial ischemia (MI) resulting in infarction is an important cause of mortality and morbidity worldwide. Acute ischaemia rapidly impairs myocardial contractile function. Myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. Hibernation is now thought to be...
[ 3 ] - Rare association of schizophrenia and unilateral Graves’ disease with contralateral thyroid hemiagenesis in two cases of McCune-Albright syndrome
The classical triad of McCune-Albright syndrome (MAS) consists of polyostotic fibrous dysplasia (FD), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction, frequently seen in females as precocious puberty. Etiology is genetically based and is explained by mosaicism of activating somatic mutations of the alpha-subunit of Gs protein. Clinical presentation is varied and is depend...
[ 4 ] - Unsuspected early necrotizing fasciitis identified by 18F-FDG PET imaging in a patient with acute myeloid leukemia
Necrotizing fasciitis is a part of a spectrum of necrotizing soft tissue infections that usually follow a surgical intervention or a chronic / acute medical illness. Diagnosis is often based on symptoms which classically start within hours after an injury. There are no reports on the use of PET/CT in this condition. Sparing reports of its association in patients with malignancy (Ca of colon and...
[ 5 ] - Combined Radionuclide Phlebography and V/Q scan in the assessment of iliac vein thrombosis and pulmonary embolism – A case report establishing a cause and effect relationship
Deep vein thrombosis (DVT) is an important life threatening condition that is difficult to diagnose, particularly in the early stages. Looking for DVT in lower limb can be considered ancillary in suspected cases of pulmonary embolism (PE) indirectly highlighting a cause and effect relationship of a single disease (i.e cause being DVT and effect is the assault on the lung vasculature). Prompt an...
[ 6 ] - 99mTc-MDP abdominal scintigraphy in a paediatric case of GI protein loss - A viable and simple alternate to HSA imaging
A nine-month old male child presented with low-grade fever, loose stools and facial puffiness. Clinically patient was otherwise normal except for a firm liver on palpation. The laboratory tests revealed hypoproteinemia (both albumin and globulin) and iron deficiency anemia. Differential diagnosis considered were: 1. Nephrotic syndrome, 2. Cystic fibrosis (in view of recurrent diarrhea and respi...
[ 7 ] - Bochdalek hernia with intrathoracic kidney as one of its contents - Incidentally identified by 99mTc-DTPA renogram
Congenital diaphragmatic hernia (CDH) is a rare anomaly with a reported incidence of 1 in 16,000 populations. It may be associated with herniation of stomach, intestinal loops, spleen, and kidney through a chest wall defect. We report a case of a 1 year old male child who presented with recurrent fever, occasional chills and rigor of 4 months duration. Left kidney was non visualised on ultrasou...
[ 8 ] - Can three-phase skeletal scintigraphy predict the outcome and determine the timing of removal of bone distracters in avascular necrosis of femur using a novel corticostomy technique?
Introduction: 99mTc-Methylene diphosphonate (99mTc-MDP) three phase bone scintigraphy (TPS) is beneficial to evaluate the success of femoral head revascularization using novel distraction osteogenesis techniques with bone muscle pedicle grafts. This pilot study was undertaken to evaluate the feasibility and utility of 99mTc-MDP three phase bone ...
[ 9 ] - Diagnostic performance of 18F-FDG PET-CT in patients presenting with secondary neck nodes from an unknown primary
Introduction: Clinical examination and even anatomical imaging may fail to identify primary site of malignancy in patients presenting with cervical nodal metastasis. 18F-Fluorodeoxyglucose Positron Emission Computed Tomography (18F-FDG PET-CT) is known to overcome the limitations of anatomic imaging. Methods: Sixty-three (63) patient...
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