karim ebrahim

[ 1 ] - The Association of Amniotic Fluid Cadmium Levels with the Risk of Preeclampsia, Prematurity and Low Birth Weight

Background: Cadmium is an extremely toxic metal with ubiquitous environmental distribution. Cadmium is a potent reproductive and developmental toxic agent, and intensive environmental exposure to this substance has been reported among the residents of Tehran. In this study, we investigated the correlation between amniotic fluid cadmium levels and the risk of preeclampsia, prematurity and low bi...

[ 2 ] - Anticancer Activity a of Caspian Cobra (Naja naja oxiana) snake Venom in Human Cancer Cell Lines Via Induction of Apoptosis

Abstract Cancer is the leading cause of death worldwide. Current anticancer drugs involve various toxic side effects; efforts are ongoing to develop new anticancer agents especially from the screening of natural compounds. Present study investigated cytotoxic effects and mode of cell death induced by the Caspian cobra venom in some human cancer cell lines. Cytotoxic effects of snake venom toxin...

[ 3 ] - Primula auriculata Extracts Exert Cytotoxic and Apoptotic Effects against HT-29 Human Colon Adenocarcinoma Cells

Primula auriculata (Tootia) is one of the most important local medicinal plants in Hamedan district, Iran. To investigate cytotoxicity and apoptosis induction of crude methanolic extract and different fraction of it we compared several methods on HT-29 human colon Adenocarcinoma cells. Cancer cell proliferation was measured by 3-(4, 5‑dimethylthiazolyl)-2, 5‑diphenyl‑tetrazolium bromide (MTT) a...

[ 4 ] - Anticancer Activity a of Caspian Cobra (Naja naja oxiana) snake Venom in Human Cancer Cell Lines Via Induction of Apoptosis

Abstract Cancer is the leading cause of death worldwide. Current anticancer drugs involve various toxic side effects; efforts are ongoing to develop new anticancer agents especially from the screening of natural compounds. Present study investigated cytotoxic effects and mode of cell death induced by the Caspian cobra venom in some human cancer cell lines. Cytotoxic effects of snake venom toxin...

[ 5 ] - Primula auriculata Extracts Exert Cytotoxic and Apoptotic Effects against HT-29 Human Colon Adenocarcinoma Cells

Primula auriculata (Tootia) is one of the most important local medicinal plants in Hamedan district, Iran. To investigate cytotoxicity and apoptosis induction of crude methanolic extract and different fraction of it we compared several methods on HT-29 human colon Adenocarcinoma cells. Cancer cell proliferation was measured by 3-(4, 5‑dimethylthiazolyl)-2, 5‑diphenyl‑tetrazolium bromide (MTT) a...

[ 6 ] - Risk of Phthalate Exposure among Hospitalized Patient via Intravenous Fluids Receiving

Background: Phthalates are widely used as plasticizers in polyethylene terephthalate (PET) products. Several pharmaceutical products have been stored in PET containers, and due to serious health effects of phthalates, migration levels of them into pharmaceutical products must be determined. In the present study, leaching levels of four common phthalate esters including di-n-butyl phthalate (DBP...

[ 7 ] - Hematological and hepatic alterations among copper mine workers and office employees in a copper mine in the west of Iran, 2015

Background: Workers in different occupational positions experience significant Cu exposures, however, Cu toxicity has not been fully studied as compared to other heavy metals. In the present study, hematological and hepatic alterations have been investigated among copper mine workers. Materials and Methods: This descriptive study was conducted in a copper mine in west of Iran, on 402 copper mi...

[ 8 ] - Occupational Exposure Rate of Staffs of Bushehr Forensic Medicine Toxicology Lab to Chloroform, Diethyl Ether and Ammonia

Abstract Background and aims: Chloroform, diethyl ether and ammonia are toxic solvents wildly used in forensic labs for preparation and extraction of samples. The staffs of forensic labs experience high levels of exposure to these solvents. Serious health effects have been reported due to exposure to these solvents including hepatotoxicity, neurotoxicity, carcinogenicity and mutagenicity. Ma...