Saeid Abediankenari
Department of Immunology and Microbiology
[ 1 ] - FOXP3 and TGF-β Gene Polymorphisms in Allergic Rhinitis
Background: Regulatory CD4+T (Treg) cells are effective in maintaining immune tolerance. Objective: To investigate single nucleotide polymorphisms (SNPs) of Transforming Growth Factor β-1 (TGF-β1) and Forkhead Box Protein 3 (FOXP3) genes in Iranian patients with allergic rhinitis (AR). Methods: Variations at codons 10 and 25 of TGF-β1 and FOXP3 at positions -3279 A>C and -924 A>G were evaluated...
[ 2 ] - Comparison of Several Maturation Inducing Factors in Dendritic Cell Differentiation
Background: Dendritic cells (DCs) are professional antigen presenting cells that have an important role in the initiation of immune response. The use of maturation factors in dendritic cell differentiation provides a promising approach in immunotherapy. Objective: In this study, we compared tumor necrosis factor-α, polyribocytidylic acid, lipopolysacharide and CpG oligonucleotides in inducing d...
[ 3 ] - بررسی اثرات 4 نوع عصاره میوه آووکادو بر روی رده سلول های اسکواموس کارسینوم مری در مقایسه با سلول های تک هسته ای خون محیطی و گروه کنترل
Background and purpose: The majority of patients with cancers of the digestive system admit themselves to the health care systems in the final stages of the disease and conventional treatments do not have a major impact on the prognosis in these patients. Therefore, utilization of new methods of treatment with lower adverse effects can cause higher survival rates. In this study, the in vitro ef...
[ 4 ] - بررسی همبستگی HbA1C با فاکتورهای خطر پروفایل لیپیدی در بیماران دیابتی نوع دو
Background and purpose: HbA1c is one of the best important markers in controlling of diabetic patients. Today, long-term assessment of blood glucose in diabetic patient's takes place by measuring glycosylated hemoglobin (HbA1C) .One of the main causes of death in diabetics is cardiovascular diseases that the increase in blood lipids and atherosclerosis is a major causes of these diseases. The a...
[ 5 ] - Human Leukocyte Antigen-G Expression on Dendritic Cells Induced by Transforming Growth Factor-β1 and CD4+ T Cells Proliferation
Background: During antigen capture and processing, mature dendritic cells (DC) express large amounts of peptide-MHC complexes and accessory molecules on their surface. DC are antigen-presenting cells that have an important role in tolerance and autoimmunity. The transforming growth factor-beta1 (TGF-β1) cytokine has a regulatory role on the immune and non-immune cells. The aim of this study is ...
[ 6 ] - ریسک فاکتورهای ابتلا به بیماری سل: گزارش کوتاه
Background: Tuberculosis is one of the most important diseases with annually 8 million new cases worldwide. The purpose of this study was to investigate the risk factors for tuberculosis (TB) infection. Methods: In this descriptive study performed in Health center of Maznadaran province during 2010-2011, 183 patients with pulmonary and extrapulmonary TB infection were recruited. After measurin...
[ 7 ] - Evaluation of Cell Growth Inhibition of Bifidobacterium Bifidum Cell-free Supernatant Extract on 4T1Tumor Cell Lineage
Background: Cancer is amongst the leading reasons of death in all parts of the world. Breast cancer is also responsible for the largest number of deaths among women population. Several studies confirmed that Bifidobacterium bifidum as a probiotic meaningfully inhibited breast cancer development. The present study aimed to investigate the effect of B. bifidum supernatant on the cell growth inhib...
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