Sepideh Darougar
Allergy Research Center | Allergy and Immunology Department, Pediatrics Ward, Shiraz University of Medical Sciences, Shiraz, Iran
[ 1 ] - Interleukin-17 Gene Expression and Serum Levels in Children with Severe Asthma
Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...
[ 2 ] - The Relationship Between Serum Interleukin-6 Level and Chronic Urticaria
Background: The immunologic profile of chronic urticaria is not only important for diagnostic purposes, but also for therapeutic approaches. This study evaluated the serum levels of Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α) and Interferon-ϒ (IFN-ϒ) in patients with chronic urticaria to find a biomarker.Materials and Methods: Forty-one patients with chronic urticaria referring to the...
[ 3 ] - Serum Interleukin-17 Evaluation in Patients With Eosinophilic Gastrointestinal Disease
Background: Eosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, inc...
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