Laszlo Pecze

Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences | Department of Medicine, University of Fribourg, Fribourg, Switzerland

[ 1 ] - Propylene-Glycol Aggravates LPS-Induced Sepsis through Production of TNF-α and IL-6

Background : Propylene glycol (1,2-propanediol, PG) is a commonly used solvent for oral, intravenous, as well as topical pharmaceutical preparations. While PG is generally considered to be safe, it has been known that large intravenous doses given over a short period of time can be toxic. Objective: To evaluate the effect of PG in sepsis induced by the bacterial endotoxin lipopolysaccharide (LP...

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