Sayed Jamaleddin Shahtaheri
School of Public Health, Center for Environmental Research, Medical Sciences / University of Tehran, Tehran, I.R. IRAN
[ 1 ] - Solid Phase Extraction for 1-Hydroxypyrene as a Biomarker of Occupational Exposure to PAHs Prior to High Performance Liquid Chromatography
Urinary 1-hydroxypyrene is frequently used as a major metabolite and biological indicator of the overall exposure to polycyclic aromatic hydrocarbons. In this study, solid phase extraction was appropriately conditioned with regard to sample pH, sample concentration, loading flow rate, elution solvent, washing solvent, sample volume and sorbent mass. Octadecyl silica cartridge (C<su...
[ 2 ] - Evaluation of Factors Inf luencing Recovery of Herbicide 2,4-D from Drinking Water
Many modern analytical methods deal with the trace-level determination of compounds of interest in highly complex environmental samples by means of chromatographic techniques. The introduction of a “clean” sample into an analytical instrument can make analyses easier and prolongs the equipment life. The use of solid-phase extraction (SPE) has grown and is a fertile technique of sample prepa...
[ 3 ] - بررسی ارتباط بین نوبت کاری با مولفه های خونی کارکنان، مطالعه موردی یک صنعت پتروشیمی
Background and aims: Today, shift working is a common in many developed countries cause industrial development and implement of service organization. This study attempts to determine the relationship between shift working and blood parameters among employees of a petrochemical company. Methods: In a cross-sectional study, the study was done with 403 workers from a petrochemical company, Iran i...
[ 4 ] - بهینه سازی روش ریز استخراج مایع مایع پخشی برای تعیین مقادیر جزیی ملاتونین بزاقی بوسیله کروماتوگرافی مایع با عملکرد عالی
Background and aims: Due to low concentration of melatonin and also the existence of other compounds in body fluids, measuring the amount of melatonin is a serious challenge for the analysts. Before measurement of melatonin amounts using chromatographic method, sample preparation is unavoidable. The aim of current study is develop a new sample preparation method that not only have high accuracy...
[ 5 ] - طراحی و توسعه یک حسگر الکتروشیمیایی اصلاح شده با پلیمر قالب مولکولی و نانولوله های کربنی به منظور ارزیابی مواجهات محیطی و شغلی با آفت کش دی‌کلران
Background and aims: Dicloran pesticide is used to inhibit the fungal spore germination for different crops. Due to the increasing application of pesticides, evaluating the occupational and environmental exposures by reliable and accurate analytical methods is necessary. This work was aimed to design the high selective sensor to determine the dicloran in biological and environmental samples. ...
[ 6 ] - ارزیابی مواجهه‌ی تنفسی شاغلین کیوسک‌های روزنامه فروشی شهر تهران با هیدروکربن‌های چند حلقه‌ای آروماتیک توسط دستگاه کروماتوگرافی گازی مجهز به آشکارساز اسپکتروفتومتر جرمی
Background and aims: Polycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds that are produced during the incomplete combustion of fossil fuels and petroleum products and are widely spread in the environment. Newsagents may be exposed to urban pollutions such as polycyclic aromatic hydrocarbons. The aim of this study was to assess the breathing zone exposure of newsagents to ...
[ 7 ] - پایش بیولوژیکی و محیطی سرب و اثرات تماس با آن در صنعت خودرو سازی
Background and Aims: Soldering is one of the most common activities in metal industries. Lead is used in soldering process and has considerable toxic effects. The aim of this study, therefore, was biological and environmental monitoring and investigating the effects of exposure to lead in soldering unit workers at an automobile industry. Methods: In order to evaluate biological and enviro...
[ 8 ] - اندازه گیری کمی و کیفی استیرن در مجتمع پتروشیمی تبریز
Background and aims Beside the vast usages of styrene in different industries, this compound can be considered as an important organic air pollutant. Styrene, in one hand, can adversely affect on workers and on the other hands can cause air pollution in the environment. In this study, Tabriz Petrochemical Complex was selected for evaluation of styrene. Methods Measurements were performe...
[ 9 ] - بهینه‌سازی روش میکرواستخراج اتیل‌بنزن موجود در نمونه‌های ادرار با استفاده از فاز جامد در ارزیابی مواجهه‌های شغلی
زمینه و هدف: روش‌های تعیین آلاینده‌های آلی در نمونه‌های آب و ادرار نیازمند استخراج آلاینده‌ها با استفاده از حلال‌های سمی و خطرناک می‌باشد. روش میکرواستخراج با استفاده از فاز جامد SPME (Solid Phase Microextraction) یک روش استخراج تعادلی است که در آن با کالیبراسیون مناسب می‌توان آلاینده‌ها را در غلظت‌های پایین و با حساسیت بسیار بالا و بدون استفاده از حلال انجام داد. از آن‌جا که ترکیبات آلی فرار (...
[ 10 ] - بهینه سازی روش میکرو استخراج مایع-مایع پخشی برای تعیین مقادیر جزیی سم دیازینون در نمونه های ادرار
Introduction: Measurement of pesticides in biological matrices is become a serious challenge for researchers due to their very low concentration in different matrices. The aim of this study was to develop a new sample preparation method with high accuracy and validity and short retention time for determination of diazinon. Material and Method: Dispersive liquid-liquid micro-extraction techniqu...
[ 11 ] - ارزیابی ریسک مواجهه با آلاینده‌های شیمیایی در یک صنعت خودروسازی
Introduction: In recent years, many national and international expert groups have considered specific improvements in risk assessment of chemical pollutants. This study considered to assess the risk of workers exposure to air pollutants in an automobile manufacturing in order to evaluate the health risk assessment due to the inhalation exposure. Material and Method: To perform this study, ...
[ 12 ] - بهینه سازی فرایند جذب فنانترن برروی نانوتیوب کربنی چنددیواره
Introduction: Polycyclic Aromatic Hydrocarbons (PAHs) belong to one of the groups of persistent organic pollutants (POPs) which are the result of incomplete combustion of organic materials, volcanic eruptions and forest and agricultural fields’ fires in the environment. However, human factors are main source of these pollutions. Nowadays, these compounds are among the main concerns related to t...
[ 13 ] - سنتز جاذب پلیمری قالب ملکولی به منظور استخراج انتخابی یک علف کش تریازینی از نمونه بیولوژیک
Background and aims: Increasing production and the use of pesticides for agricultural purposes can lead to many environmental and human health risks. Therefore, assessment of their concentration in occupational and environmental samples is necessary to estimate exposure levels. This study was aimed to use a synthesized molecular imprinted polymer (MIP) as a novel and specific absorbent for resi...
[ 14 ] - ارزیابی تاثیر تغییرات فصلی بر میزان مواجهه شاغلین کیوسک های روزنامه فروشی با هیدروکربن‌های چند حلقه ای آروماتیک موجود در هوای شهر تهران
Background and Objectives: PAHs are main components of urban air pollution and are mutagenic for human being. Seasonal variations have effects on the amount of exposure to PAHs. The objectives of this research were to determine the amount of newsagent’s exposure to PAHs found in the urban atmosphere of Tehran City during warm and cold periods and comparing exposure levels in two periods. Materi...
[ 15 ] - روند یکساله میزان مواجهه رانندگان تاکسی شهر تهران با مونوکسیدکربن
Background and Aim: Motor vehicles are an absolute necessity used extensively in all countries of the world. They are a major cause of air pollution with highly undesirable consequences. Thus, exposure to traffic pollution is a growing public health concern. Several studies indicate that people in the cabin of a vehicle inhale air with high concentrations of pollutants such as nitrogen oxides...
[ 16 ] - کاربرد پلیمر قالب یونی به منظور توسعه پایش زیست شناختی کادمیوم در یک صنعت خودروسازی
Background and Aim: Exposure to heavy metals always causes serious health problems in people working in the industry. Heavy metals may interfere with enzyme functioning or accumulate in specific body organs, leading to various health problems. Cadmium is a toxic heavy metal widely used in various industries and, therefore, workers in metal industries are at risk of exposure to it. Materials...
[ 17 ] - تعیین شاخص‌های سم شناسی کربن نانوتیوب و کریزوتایل بر اساس سمیت سلولی در سلول‌های اپیتلیال ریه انسان به صورت اینویترو
Background and aim: In this study the cytotoxicity to human epithelial lung cells of single-walled carbon nanotubes, multi-walled carbon nanotubes and chrysotile was compared based on the following cytotoxicity indices: no observable adverse effect concentration (NOAEC), inhibitory concentration 50 (IC50), and Total Lethal Concentration (TLC). Materials and Methods: Human epithelial lung cells...
[ 18 ] - Synthesis and optimization of application of a molecular imprinted sorbent for selective determination of two pyrethroid isomers from biological sample
Introduction: Along with the extensive production and use of various pesticides for controlling pests and enhancing the production of agricultural crops, there is a growing concern about the adverse effects of these toxic materials on human health. Therefore, the development of sensitive, selective, and accurate methods for continuous assessment of pesticides concentration in occupational and e...
[ 19 ] - Investigation of hydrogen sulfide adsorption in metallic scaffold MOF-5 nanocomposite based on activated carbon for the use of respiratory mask cartridge
Introduction: Hydrogen sulfide is one of the most important impurities in natural gas. Due to the fact that this gas is hazardous, toxic, corrosive and volatile, therefore, the removal of hydrogen sulfide has been studied using several methods. One of the most known procedures is the adsorption process. In the present study, activated carbon and activated carbon-based composite scaffolds (MOF-5...
[ 20 ] - Protective Effect of Salvia officinalis Extract on Deltamethrin-induced Hepatotoxicity in Rats
Background and purpose: Deltamethrin is one of the major pesticides used in agriculture to control pests. Oxidative stress is one of the deltamethrin toxicity mechanisms. Different antioxidants have been investigated to deal with the oxidative damage of toxic substances. The purpose of this study was to evaluate the protective effect of Salvia officinalis extract against deltamethrin-induced he...
[ 21 ] - Antioxidant and Protective Effects of Plant Extract against Deltamethrin-induced Oxidative Stress in Liver and Kidney – A Review
Deltamethrin is one of the most commonly used Pyrethroid around the world. Oxidative stress is one of the most deltamethrin toxicity mechanisms. According to many studies, it has been shown that the liver, due to its role, is the main source of accumulation of high concentrations of deltamethrin metabolites. Also the kidney plays a very important role in regulating homeostasis of the body and r...
[ 22 ] - Study of the dynamic adsorption process of toluene by a microporous copper metal-organic framework
Introduction: Toluene is considered as a group of chemical contaminants, causing problems for people’s health. Due to the high rate of evaporation and rapid emission in the surrounding environment, it leads to the exposure of many employees and people at risk and, subsequently, its irreparable effects on their health in different jobs. Therefore, its removal is very important. In the present st...
[ 23 ] - Development of A Sample Preparation Method for evaluating Trace Residue of Bentazon Pesticide in Biological Matrices Using Dispersive Solid Phase Extraction (SPE) Method Based on Molecular Imprinted Polymer (MIP)
Introduction: Pesticides are among the broadest chemical compounds used in the world and are also considered as the most dangerous compounds for living organisms. Although pesticides have significant impact on improving agricultural and food products, the processes of their production, formulation, storage, transportation, and marketing as well as the extensive use of these materials lead to oc...
[ 24 ] - The protective effect of rosemary in mitigating oxidative stress induced by Chlorpyrifos in rat kidney
Introduction: Chlorpyrifos is an organophosphorus insecticide that can produce reactive oxygen species, and oxidative stress in the kidney. On the other hand, rosemary extract is an antioxidant playing a protective role against free radicals. Therefore, the aim of this study was to evaluate the oxidative stress in rat kidney due to the exposure to chlorpyrifos and to assess the antioxidant effe...
[ 25 ] - Investigating the protective effects of aqueous extract of the wormwood plant (Artemisia absinthium) on alumina nanoparticle-induced pulmonary toxicity in male Wistar rats
Introduction: Although aluminum oxide nanoparticles (Al2O3-NPs) are the most widely used nanomaterials, limited studies have been reported on their toxicology. Therefore, the present study aimed to investigate the potential toxicity of aluminum oxide (alumina) nanoparticles and the protective role of aqueous extract of wormwood plant on nanomaterial-induced disorders in the lung of rats. Mater...
[ 26 ] - DEVELOPMENT OF A PHYSIOLOGICALLY BASED TOXICOKINETIC MODEL FOR HUMAN EXPOSURE RISK ASSESSMENT OF METHYLENE DIPHENYL DIISOCYANATE(MDI)
Introduction: Given the lack of a developed physiologically based toxicokinetic (PBTK) model for human systemic exposure assessment of methylene diisocyanate (MDI) and prediction of its urinary metabolites, this study aims to develop a PBTK model for exposure risk assessment of MDI. Methods and Materials: In this study, to assess the potential exposure to the MDI, a PBTK model was constructed ...
[ 27 ] - OCCUPATIONAL EXPOSURE TO COMMON TOXICANTS IN WORKPLACEs AND ITS IMPACT ON SUSTAINABLE DEVELOPMENT WITH EMPHASIS ON MAINTENANCE AND PROMOTION OF WORKERS' HEALTH: A REVIEW
Introduction: Chemicals are necessary for many economic activities and daily life. However, they can create noxious effects on individuals. It is required more attention to human (worker) health on the route of attainment of sustainable development. The present study reviews the studies done in the field of the effect of toxicants on workers' health. Also, the study investigated the role of tox...
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