Abbas Shafiee
Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, I.R. IRAN
[ 1 ] - Brønsted Acidic Phosphonium Based Ionic Liquid Functionalized SBA-15 [HO3S-PhospIL@SBA-15]: Green, Recyclable, and Efficient Catalyst for the Synthesis of Pyrano[3,2-c]Chromenone Derivatives
The surface of SBA-15 was modified by diphenylphosphine; then, it was treated with butane sultone and sulfuric acid to obtain Brønsted acid HO3S-phosphonium based ionic liquid functionalized SBA-15 with HSO4- as a counteranion. It efficiently catalyzed synthesis of pyrano[3,2-c]chromenone derivatives through the reaction of 4-hydroxycoumarin and chalcones at...
[ 2 ] - Volatile Constituents and Antimicrobial Activity of Zataria Multiflora, Population Iran
The essential oils of Zataria multiflora (Labiatae) from four regions of Iran were investigated by GLC and GC-MS methods. The main constituents were carvacrol, thymol, linalool and p-cymene. The percentage of the constituents (in dry and wet plant) of different regions have been compared. Antibacterial and antifungal effects of these essential oils have been studied. The essential oil with ...
[ 3 ] - Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles
The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl-2-isoxazolines.
[ 4 ] - Syntheses, Antibacterial and Antifungal Activities of Substituted-Thiazolo-1,3,4-Thiadiazoles, 1,3,4-Oxadiazoles and 1,2,4-Thiazoles
Starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), The title compounds were prepared. The reaction of compound 1 (R=CH3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). Refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pen...
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