Mohsen Naseri
Department of Pharmacology and Department of Iranian Traditional Medicine, Medical School, Shahed University, Tehran, Iran
[ 1 ] - The Effect of MS14 on Production of Pro-inflammatory Cytokines by Macrophages
Objective(s) Using herbal medicines as a complementary treatment method is increasing in wide variety of diseases. MS14-an herbal-marine preparation-is reported to have anti-inflammatory and immunomodulatory activities; however, the mechanism underlying its therapeutic effect is not known. Macrophages play an important role in host defense mechanisms and carry out their role by producing vario...
[ 2 ] - The Study of Anti-Inflammatory Activity of Oil-Based Dill (Anethum graveolens L.) Extract Used Topically in Formalin-Induced Inflammation Male Rat Paw
Inflammation is one of the symptoms of many common and harmful diseases. As it is incurable through chemical drugs, the study on this ailment using new methods and drugs seems necessary. In addition, the adverse effects of the present anti-inflammatory drugs like NSAIDS and Glucocorticoid appeared in the long time use make such study more demanded. Accordingly, in this study we examined the eff...
[ 3 ] - The Study of Anti-Inflammatory Activity of Oil-Based Dill (Anethum graveolens L.) Extract Used Topically in Formalin-Induced Inflammation Male Rat Paw
Inflammation is one of the symptoms of many common and harmful diseases. As it is incurable through chemical drugs, the study on this ailment using new methods and drugs seems necessary. In addition, the adverse effects of the present anti-inflammatory drugs like NSAIDS and Glucocorticoid appeared in the long time use make such study more demanded. Accordingly, in this study we examined the eff...
[ 4 ] - نظریه‌ی مزاج در طب سنّتی ایران و تنوّع پاسخ‌دهی درمانی بر اساس فارماکوژنتیک
دانش ژنتیک و فیزیوپاتولوژی نشان‌داده است که بروز یک بیماری می‌تواند ناشی از علل مختلفی مانند جهش در ژن‌های مختلف و مکانیسم‌های متفاوت مولکولی باشد، در‌حالی‌که ممکن است در بالین، علایم به‌ظاهر یکسانی مشاهده شود. از طرفی بیماران از‌نظر جذب داروها، تاثیر، کارآیی و عوارض جانبی آن‌ها، واکنش‌های مختلفی به یک دارو نشان می‌دهند و همین مساله باعث شده است تا پزشکان هنگام تجویز دارو برای بیمار، علاوه بر...
[ 5 ] - تاثیر ماساژ بازتابی پا بر شاخص های فیزیولوژیک بیماران تحت عمل جراحی بای پس عروق کرونر
Introduction: A common problem in patients undergoing coronary artery bypass surgery is changes in physiological indexes following anxiety and pain due to surgery, which have negative consequences. This study was conducted to investigate the effect of foot reflexology massage on physiological indexes of patients undergoing coronary artery bypass surgery. Methods: This randomized clinical tr...
[ 6 ] - بررسی انواع و علل دردهای مفصلی در متون طب سنتی ایران
Background & Aims: Oja-e-mafasel is an important issue of Iranian Traditional Medicine (ITM) with high prevalence, high costs, and severe disabilities that affects the society. In modern medicine treatment of joint pain in most cases is limited to symptomatic treatment and pain control, but in ITM, treatment protocol is performed according to pain mechanisms. Materials & Methods: This study...
[ 7 ] - اثر ضدالتهابی پماد مرهم مفاصل در موش‌های صحرایی نر
زمینه و هدف: التهاب، پاسخ محافظتی میزبان در برابر عوامل مهاجم خارجی و بافت نکروزی است که می‌تواند باعث آسیبهای بافتی شود. در تحقیق حاضر اثر ضدالتهابی پماد مرهم مفاصل]شامل گیاهان بابونه و ابوخلسا (هواچوبه)[، مورد بررسی قرار گرفت. روش بررسی: در این مطالعه 72 سر موش صحرایی نر به سه گروه شامل: کنترل،التهاب، التهاب- درمان تقسیم شدند. برای ایجاد التهاب، از تزریق فرمالین به کف پای حیوان، تزریق گزیلن ...
[ 8 ] - Anti-hemorrhagic activity of Punicagranatum L. flower (Persian Golnar) against heavy menstrual bleeding of endometrial origin: a double-blind, randomized controlled trial
Background: Heavy menstrual bleeding of endometrial origin (HMB) is a major healthcare problem in premenopausal women and affects several aspects of women’s health and quality of life (QoL). The aim of this study was to compare the efficacy of Persian Golnar (PG) and tranexamic acid (TA) on heavy menstrual bleeding of endometrial origin (HMB) and patients’ QoL. Methods : A double-blind rand...
[ 9 ] - Anti-microbial effect of Nigella sativa seed extract against staphylococcal skin Infection
Background : The development of microbial resistance to the existing anti-microbial agents has become a real challenge and a serious problem facing patients suffering from skin infections. Seeds of Nigella sativa have been used for a long time in folk medicine for the treatment of skin infections. Production of new potent agents is urgently needed, especially for hospitals and health care cen...
[ 10 ] - A novel isolated dual perfusion/superfusion heart model for physiological and pharmacological evaluation of mammalian heart preparations
Abstract Introduction: Isolated perfused heart models such as perfusion and superfusion are commonly used for mammalian heart research. However, there are several fundamental limitations in the current techniques. In perfusion model, a suitable cannula is connected to the aorta and the perfusion is retrogradely performed. But, electrode displacement is a potential unwanted event resulted fr...
[ 11 ] - اثر عصاره هیدروالکلی ریزوم سعد کوفی بر حافظه و یادگیری موش صحرایی نر
مقدمه: به دلیل شیوع بیماری هایی نظیر آلزایمر و وجود عوارض زیاد داروهای سنتتیک، استفاده از گیاهان داروئی مورد توجه قرار گرفته است. استفاده از سعد کوفی در طب سنتی به منظور تقویت حافظه و این که تاکنون تحقیقی راجع به اثر عصاره ریزوم های گیاه سعد کوفی بر حافظه و یادگیری صورت نگرفته است، مطالعه حاضر با هدف بررسی تاثیر عصاره ریزوم سعد کوفی بر یادگیری و حافظه انجام شد. مواد و روش ها: بدین منظور...
[ 12 ] - اثر عصاره هیدروالکلی گیاه سعد کوفی Cyperus rotundusبر درد در موش های صحرایی نر دیابتی
Background and Aim: Hyperalgesiua is a symptom of neuropathy due to diabetes. The present study aimed at investigating . antineurologic effect of hydroalcoholic extract of Cyperus Rotundus in diabetic rats. Materials and Methods: In this experimental study, the rats were randomly divided into seven equal groups i.e. control, Cyperus Rotundus treated control (dose 100mg/kg), diabetic, diabetic r...
[ 13 ] - From Datura stramonium L to Hab-o-shefa: manuscript, animal and clinical studies for the treatment of addiction
Background: Due to the lack of drug dependence prevention processes and the low effectiveness of treatment for the withdrawal of addiction and undesirable side effects of synthetic drugs, moving towards the use of reverse pharmacology to produce a less costly, effective, and low-risk drug is inevitable. Objective: Considering the long history of traditional medicine in Iran in the field of diag...
[ 14 ] - Preliminary phytochemical and physicochemical study of Cuscuta chinensis L. aqueous extract
Introduction: Cuscuta chinensis L. is a widely used medicinal plant with little data on its standardization. This study aims to contribute to the efficiency and safety of its use by preliminary investigation on its physicochemical and phytochemical characteristics. Method: The extract was concentrated at low temperature to prepare a dry powder. Sensory evaluation was used to determine the orga...
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