Alijan Tabarraei

[ 1 ] - Mutations in pre-core and basal-core promoter regions of hepatitis B virus in chronic HBV patients from Golestan, Iran

Objective(s): It has been reported that the mutation of the pre-core (PC) and basal-core promoter (BCP) may play an important role in the development of HBV-related hepatocellular carcinoma (HCC). In this study the PC and BCP mutations were investigated in chronic HBV patients. Materials and Methods:In this study, 120 chronic HBV patients from Golestan, Northeast of Iran who were not vaccinated...

[ 2 ] - Population-based Seroprevalence of HTLV-I Infection in Golestan Province, South East of Caspian Sea, Iran

[ 3 ] - شیوع استافیلوکوکوس اوریوس در بینی دانش آموزان سالم دبستانی شهرستان گرگان

استافیلوکوک طلایی یکی ازشایع ترین عوامل مؤثر در عفونت های پوستی و سیستمیک می باشد. به طور طبیعی بیش از 30 درصد افراد، ناقل این باکتری در پوست و بینی خویش می باشند. افزایش روز افزون مقاومت داروئی در این باکتری ها و به تبع آن، گسترش عفونت های ناشی از آن، توجه مجامع علمی را معطوف به خود نموده است. به همین دلیل، بر آن شدیم میزان شیوع ناقلین طبیعی استافیلوکوک طلایی را در بینی کودکان سالم دبستانی شهر...

[ 4 ] - Detection of CMV and EBV DNA in PBMCs of MS Patients and Healthy Individuals in Gorgan, Iran

Background and Aims: Multiple Sclerosis is a chronic and autoimmune disease, which causes inflammation and demyelination of the axons in CNS. Studies have indicated that Herpesviruses might be one of the potential environmental elements that can trigger the initiation of the inflammatory cascade in MS. The purpose of this study was to determine whether the genome of CMV and (or) EBV is present ...

[ 5 ] - Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran

Background and Aims: Hepatitis E virus is a public health concern and about a third of people in the world live in endemic areas. Although HEV is believed to be transmitted by fecal-oral routes between humans in low sanitary conditions, but evidence of transmission have been reported in hemodialysis (HD) patients. Materials and Methods: Aim of present study was to determine the prevalence of a...

[ 6 ] - HHV-6 DNA and Antibody Detection in Plasma and PBMC of Multiple Sclerosis Patients in North of Iran

Abstract Background and Aims: Multiple sclerosis (MS) is defined by the presence of inflammatory demyelinating plaques in the central nervous system (CNS). It has been indicated that human herpes virus 6 (HHV-6) may play role in pathogenesis of MS. The aim of this study was to determine the presence of HHV-6 DNA and anti HHV-6 IgG in MS patients and controls. Materials and Methods: Bloo...

[ 7 ] - Expression Analysis of Cellular Mir-29a and mir-29b in HIV Positive Patients

Abstract        Background and Objective: Various cellular factors affect the process of HIV activity. One of these cellular factors are structures known as microRN that are expected to be involved in controlling HIV replication and infectivity. The expression of one or a set of them may represent the patient's clinical conditions. In this study, ...

[ 8 ] - Optimization of PCR-ELISA in Detection of Human Cytomegalovirus Infection

Abstract Background and Objective: Human Cytomegalovirus (CMV) is an important cause of congenital viral infection that can lead to serious diseases and complications in infants. Application of rapid, sensitive, and specific HCMV detection methods is necessary for congenital infection detection. We aimed to optimize the use of PCR and ELISA for detection of HCMV in infants. Material and Methods...

[ 9 ] - Cytomegalovirus Active Infection in Persons Infected with Human Immunodeficiency Virus

Background and Objective: Cytomegalovirus (CMV), one of the most common opportunistic pathogens in patients infected with human immunodeficiency virus (HIV), can cause the diseases such as encephalitis, pneumonia, and chorioretinitis. This study aimed at molecular studying of CMV infection in individuals infected with the human immunodeficiency virus. Material and Methods: In this study, 50 ven...

[ 10 ] - Occult Hepatitis B Virus Infection in Chronic Hemodialysis Patients in Panje-Azar Hospital, Gorgan

Abstract Background and objectives: Hepatitis B virus infection is a major health problem in worldwide. The prevalence of Occult and chronic HBV in hemodialysis patients is higher than standard in developing countries. People with occult HBV are negative for HBV surface antigen (HBsAg) but positive for HBV-DNA. We aimed to evaluate occult hepatitis B infection in patients under hemodialysis in ...

[ 11 ] - Meningitis caused by mumps virus in children admitted to Gorgan’s Taleghani hospital

Abstract Background and objectives: Mumps virus is one of the first known causative agents of meningitis in children. On-time diagnosis is the first step in treating meningitis. We aimed to evaluate Mumps virus meningitis in children in Gorgan, Iran Material and Methods: CSF and blood samples were taken from children with meningitis, Jun 2008 till Sep 2010. For 40 samples with negative bacteria...

[ 12 ] - Antitumor Immunity Induced by Genetic Immunization with Chitosan Nanoparticle Formulated Adjuvanted for HPV-16 E7 DNA Vaccine

[ 13 ] - Frequency of Human Herpesvirus 6 (HHV-6) in Pterygium Using Real-Time PCR Based on SYBR-Green I Fluorescence

ABSTRACT             Background and objectives: Pterygium is a non-cancerous growth of conjunctival tissue that can extend onto the corneal surface. The presence of some oncogenic viruses in pterygium and the neoplastic nature of these lesions led us to the postulated involvement of the viruses in the etiology of pterygium. Given the association of human herpesvirus 6 (HHV-6) with ocular disea...

[ 14 ] - Investigating the Possibility of the Listeria Monocytogenes Entering Into a Viable But Non-Culturable (VBNC) Form and Expression of the Pathogenic Genes During the Frozen Storage of (-18ºC) Rainbow Trout Fish Nugget

Background and Aims: The purpose of this study was to investigate the possibility of Listeria monocytogenes entering the VBNC state during the frozen storage and the expression of its pathogenic genes Materials and Methods: Bacteria in 106 Colony counts of in mid log phase were inoculated into three Culture medium including Normal Saline (NS), BHI Broth and Fish Broth (FB) and kept at -18ºCfor...