Moazamehosadat Razavinasab
Physiology Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - Gender difference in motor impairments induced by chronic administration of vinblastine
Objective(s):Neurotoxicity of anticancer drugs complicates treatment of cancer patients. Vinblastine (VBL) is reported to induce motor and cognitive impairments in patients receiving chronic low-dose regimen. Materials and Methods: The effects of VBL treatment on motor, learning and memory functions of male and female Wistar rats were studied by behavioral related tests. Animals were given chro...
[ 2 ] - Nitric oxide system modulates hyperalgesia and memory impairments following psycophysical stress
Introduction: Sub-chronic swim stress is known to induce a prolonged hyperalgesia, which is mediated through NMDA and opioid systems. Nitric oxide is a soluble gas, which acts as a retrograde messenger that modulates the release of mentioned neurotransmitters. It is also involved in nociception and memory. The aim of this study was to evaluate the role of NO pathway in nociception and memory...
[ 3 ] - Effect of Acute administration of Cisplatin on memory, motor learning, balance and explorative behaviours in Rats
Introduction: For some cancer survivors chemotherapy treatment is associated with lasting motor and cognitive impairments, long after treatment cessation. Cisplatin as an anti-neoplastic agent is extremely toxic and can cause severe tissue damage. In the present study, we elucidated alteration in performance of hippocampus- and cerebellum-related behaviors following acute cisplatin treatmen...
[ 4 ] - Chronic Exposure to Morphine Leads to a Reduced Affective Pain Response in the Presence of Hyperalgesia in an Animal Model of Empathy
Background: Empathy is the capability to represent the mental and emotional states of other subjects.Previous studies have demonstrated a possible correlation between morphine addiction and altered empathyresponse in morphine-addicted subjects. This study was performed to evaluate the effect of chronic morphineexposure as an animal model of morphine addiction on empathic changes in affective an...
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