Seyed Javad Mowla

[ 1 ] - Potential roles of 5´ UTR and 3´ UTR regions in post-trans-criptional regulation of mouse Oct4 gene in BMSC and P19 cells

Objective(s):OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to gene regulation. In this study, we aimed to investigate the potential regulatory role played by 5´UT...

[ 2 ] - No Detection of Crimean Congo Hemorrhagic Fever (CCHF) Virus in Ticks from Kerman Province of Iran

Introduction: Crimean Congo Hemorrhagic Fever (CCHF) is a fatal tick-borne viral zoonosis with a case fatality rate of 5% to 30%. CCHF has been documented as the most frequent tick-borne viral infection in Iran with more than 50 cases annually. Kerman Province in the south of Iran is one of the CCHF-endemic areas of the country, but no data on infection of ticks with this virus from this area i...

[ 3 ] - Extracellular Vesicles as Neprilysin Delivery Syemory Improvement of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative brain disorder which has no effective treatment yet due to the blood barrier in the brain that limits the drugs with the potential of disease improvement. Extracellular vesicles (EVs) are biocompatible nanoparticles with a lipid membrane. These vesicles are secreted from various cells such as mesenchymal stem cells (MSCs) and can pass through biol...

[ 4 ] - Extracellular Vesicles as Neprilysin Delivery Syemory Improvement of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative brain disorder which has no effective treatment yet due to the blood barrier in the brain that limits the drugs with the potential of disease improvement. Extracellular vesicles (EVs) are biocompatible nanoparticles with a lipid membrane. These vesicles are secreted from various cells such as mesenchymal stem cells (MSCs) and can pass through biol...