Massoud Houshmand

Department of Medical Genetics, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran

[ 1 ] - The mitochondrial DNA mutations associated with cardiac arrhythmia investigated in an LQTS family

Objective(s): As mitochondrial oxidative stress is probably entailed in ATP production, a candidate modifier factor for the long QT syndrome (LQTS) could be mitochondrial DNA (mtDNA). It has been notified that ion channels' activities in cardiomyocytes are sensitive to the ATP level. Materials and Methods: The sample of the research was an Iranian family with LQTS for mutations by PCR-SSCP and...

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