Nima Sanadgol
Department of Biology, Faculty of Science, University of Zabol, Zabol, Iran. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
[ 1 ] - In vitro differentiation of rat mesenchymal stem cells to hepatocyte lineage
Objective(s): Mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. Recently, mesenchymal stem cells (MSCs), as adult stem cells (ASCs) able to divide into a variety of different cells, are of utmost importance for stem cell research. In this research, ability of the liver extract to induce differentiation of rat derived omentum tissue mesenchyma...
[ 2 ] - بررسی غلاف میلین و پروتئینهای مرتبط با آن (MAG، MOG، MBP و PLP) طی تخریب میلین القا شده توسط کوپریزون در سیستم عصبی مرکزی موشهای نر نژاد C57BL/6
هدف: هدف تحقیق، بررسی دقیق اثرات وابسته بهزمان کوپریزون بر پروتئینهای MAG، MOG، MBP و PLP و روند تخریب میلین میباشد. مواد و روشها: مدل تخریب میلین با...
[ 3 ] - Capability of Cartilage Extract to In Vitro Differentiation of Rat Mesenchymal Stem Cells (MSCs) to Chondrocyte Lineage
The importance of mesenchymal stem cells (MSCs), as adult stem cells (ASCs) able to divide into a variety of different cells is of utmost importance for stem cell researches. In this study, the ability of cartilage extract to induce differentiation of rat derived omentum tissue MSCs (rOT-MSCs) into chondrocyte cells (CCs) was investigated. After isolation of rOT-MSCs, they were co-cultured with...
[ 5 ] - ارزیابی الگوهای بیان ژن مشتق از ریزآرایه در مدلهای موشی تراژن بیماری آلزایمر (تائو و آمیلوئید بتا) با استفاده از ابزارهای زیست دادهورزی
هدف: در این پژوهش تغییرات بیان ژن و تاثیر آن بر شبکههای پروتئینی، عوامل رونویسی، مسیرهای سلولی و RNAهای کوچک در مدلهای موشی تراژن بیماری آلزایمر (آمیلوئید بتا و تائو) بررسی شد.مواد و روشها: نتایج دادههای ریز آرایه ژنهای بافت مغز در پایگاه داده GEO تجزیه و تحلیل، پیش بینی شبکهها بهکمک پایگاه داده String انجام و توسط نرم افزار Cytoscape آنالیز شد. پی...
[ 6 ] - Assessing the Association Between Fennel (Foeniculum Vulgare) Extract and Serum Lipid Profile and Leptin Receptor Expression
Introduction:Obesity is one of the most serious challenges of our era, with significant health consequences and high economic burden for health systems. Therefore, many countries have developed political agendas to cope with this ever-rising challenge. Along with chemical medications that are developed to manage obesity, researchers have focused on some natural ingredients and herbal extracts w...
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