Ali Mohammadi Karakani
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
[ 1 ] - Inhibitory effect of corcin on aggregation of 1N/4R human tau protein in vitro
Objective(s):Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder. One of the hallmarks of AD is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. In this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in AD and tauopathies. Unfortunately, the available syntheti...
[ 2 ] - Evaluation of urinary enzymes in newborns treated with gentamicin
Objective(s): In recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. We examined the practical applicability of the urinary levels of NAG (N-acetyl-β-D-glucosaminidase), AP (alkaline phosphatase), and LDH (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...