Ezzat Dadkhah
School of Systems Biology, George Mason University, Manassas, Virginia, U.S.A
[ 1 ] - Loss of heterozygosity and microsatellite instability as predictive markers among Iranian esophageal cancer patients
Objective(s): Variation in microsatellite sequences that are dispersed in the genome has been linked to a deficiency in cellular mismatch repair system and defects in several genes of this system are involved in carcinogenesis. Our aim in this study was to illustrate microsatellite DNA alteration in esophageal cancer. Materials and Methods: DNA was extracted from formalin fixed paraffin embedde...
[ 2 ] - Informative STR Markers for Marfan Syndrome in Birjand, Iran
Objective(s)Marfan syndrome (MFS) is a severe connective tissue disorder withan autosomal dominant inheritance pattern. Early diagnosis is critical in MFS. Because of the large size of fibrillin-1 gene (FBN1), the uniqueness of mutations, and the absence of genotype-to-phenotype correlations linkage analysis can be very helpful for early diagnosis of MFS. In this study, eight polymorphic marker...
نویسندگان همکار