Ali Asghar Kiani

Razi Herbal Medicines Research Center and School of Allied Medical Sciences, Department of Hematology and Blood Transfusion, Lorestan University of Medical Sciences, Khorramabad, Iran

[ 1 ] - Cxcr4 expression is associated with time–course permanent and temporary myocardial infarction in rats

Objective(s): Experimental myocardial infarction triggers secretion of Stromal cell-derived factor1 and lead to increase in the expression of its receptor "CXCR4" on the surface of various cells. The aim of this study was to evaluate the expression pattern of CXCR4 in peripheral blood cells following time-course permanent and temporary ischemia in rats. Materials and Methods: Fourteen male Wist...

[ 2 ] - The prevalence of the ABO hemolytic disease of the newborn and its complications in an Iranian population

Background: ABO incompatibility is the most common cause of immune hemolytic disease of the newborn (HDN) and in most cases is not dangerous. The present study aimed to determine the prevalence of ABO-HDN and its effects on neonatal blood parameters in a population of patients referred to some training hospitals in Iran. Materials and methods: In This cross-sectional study, All newborns (a tot...

[ 3 ] - طراحی و ساخت سازه‌ ژنی نوترکیب بیان کننده ژن حفاظت کننده سلولی

Background : Genetic manipulation is an effective strategy to protect cells against environmental damages and enhance their capabilities for therapeutic usage. In order to avoid unwanted side effects, such as cancers, the expression of genes should be temporary increased. The aim of this study was to clone and temporary increased expression of a cell protective gene, Metallothionein 1 (MT1) in ...

[ 4 ] - Association study between DNA methylation and genetic variation of APOE gene with the risk of coronary artery disease

Coronary artery disease (CAD) is a common health problem with a high rate of disability and death. Dyslipidemia and altered metabolism of Apo-lipoproteins are involved in the CAD pathogenesis. The current study investigated two common polymorphisms (rs429358 and rs7412) and promoter DNA methylation status of APOE in the Iranian CAD patients and control subjects. Two hundred angiographi...