Seyed Mohammad Abedi

[ 1 ] - 99mTc-Glucarate for assessment of paclitaxel therapy in human ovarian cancer in mice

Objectives: The monitoring of cancer treatment response to chemotherapy is considered an essential strategy for follow-up of patients. The aim of this study was to evaluate the use of 99mTc-glucarate as a radiotracer for in vivo quantification and visualization of necrotic area and therapeutic effect of paclitaxel in ovarian cancer xenografted nude mice. Materials and Methods: After implantatio...

[ 2 ] - Radioprotective effect of thymol against salivary glands dysfunction induced by ionizing radiation in rats

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to radiation at dose 15Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

[ 3 ] - Radioprotective effect of thymol against salivary glands dysfunction induced by ionizing radiation in rats

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to radiation at dose 15Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

[ 4 ] - Beneficial effects of Pimpinella anisum L. ethanol and aqueous extracts on L-asparaginase-associated hepatotoxicity using specific 99mTc-Phytate biodistribution studies in rats

Introduction: The present study aimed to investigate the protective effects of Pimpinella anisum L. ethanolic and aqueous extracts on L-asparaginase- associated hepatotoxicity in rats using histopathological and specific 99mTc-Phytate biodistribution studies. Materials and Methods: 60 female rats were divided into 9 treatment groups including L-asparaginase group, Aqueous extract (100 and 200 m...