Xiaoxia Zhu

Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China

[ 1 ] - S100A9 aggravates bleomycin-induced dermal fibrosis in mice via activation of ERK1/2 MAPK and NF-κB pathways

Objective(s): This study aims to investigate the pathogenicity and possible mechanisms of S100A9 function in mice models of scleroderma. Materials and Methods: The content of S100A9 in the skin tissues of mice with scleroderma was determined. Different concentrations of bleomycin (BLM) and S100A9 were subcutaneously injected into the backs of mice simultaneously, and then pathological changes i...

نویسندگان همکار

Cheng Zhao 1  

Dandan Wang 1  

Hejian Zou 1  

Jiucun Wang 1  

Jun Liang 1  

Lingyun Sun 1  

Xue Xu 1  

Xuebing Feng 1  

Zhiyong Chen 1