Gholam Hossein Meftahi
Neuroscience Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran
[ 1 ] - Deep brain stimulation in a rat model of post-traumatic stress disorder modifies forebrain neuronal activity and serum corticosterone
Objective(s): Post-traumatic stress disorder (PTSD), one of the most devastating kinds of anxiety disorders, is the consequence of a traumatic event followed by intense fear. In rats with contextual fear conditioning (CFC), a model of PTSD caused by CFC (electrical foot shock chamber), deep brain stimulation (DBS) alleviates CFC abnormalities.Materials and Methods: Forty Male Wistar rats (220–2...
[ 2 ] - Effects of the Extremely Low Frequency Electromagnetic Fields on NMDA-Receptor Gene Expression and Visual Working Memory in Male Rhesus Macaques
Introduction: The present research aimed to examine Visual Working Memory (VWM) test scores, as well as hormonal, genomic, and brain anatomic changes in the male rhesus macaques exposed to Extremely Low Frequency Magnetic Field (ELF-MF). Methods: Four monkeys were exposed to two different ELF-MF frequencies: 1 Hz (control) and 12 Hz (experiment) with 0.7 µT (magnitude) 4 h/d for 30 conse...
[ 3 ] - Review Paper: Role of Nitric Oxide on Dopamine Release and Morphine-Dependency
The catastrophic effects of opioids use on public health and the economy are documented clearly in numerous studies. Repeated morphine administration can lead to either a decrease (tolerance) or an increase (sensitization) in its behavioral and rewarding effects. Morphine-induced sensitization is a major problem and plays an important role in abuse of the opioid drugs. Studies reported that mor...
[ 4 ] - Effect of Transient Inactivation of Ventral Tegmental Area on the Expression and Acquisition of Nicotine-Induced Conditioned Place Preference in Rats
Background: Nicotine can activate dopaminergic neurons within the ventral tegmental area (VTA). However, there is no evidence about complete inhibition of VTA on nicotine reinforcement. Methods: in the present study, we used conditioned-place preference (CPP) method to study the effect of transient inhibition of left and/or right side of the VTA by lidocaine on nicotine reward properties. Male ...
[ 5 ] - Effects of resveratrol on intrinsic neuronal properties of CA1 pyramidal neurons in rat hippocampal slices
Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...
[ 6 ] - تعارض ارزشهای فرد و جامعه با رویکرد علوم شناختی و راهکارهای کاهش آن برای افزایش سلامت روانی؛ یک مطالعه نظریه پردازی
Classification of human value are based on the understanding experiences (physical and emotional) and education. The grading of values and beliefs are dependent to receiving bonuses and avoid damaging which change during life. If the person see conflicts between his believes and past educations with what’s happening go on inconsistency. Site of identifying conflicts and or high risk selec...
[ 7 ] - ارزیابی نقش 2-اکسو 4-تیازولیدین-کربوکسیلیک اسید (OTC) بر کسب و بیان وابستگی به مورفین در موشهای نژاد NMRI نر
سابقه و هدف: در طی وابستگی به مورفین غلظت آنتی‌اکسیدان‌های طبیعی کاهش می‌یابد که یکی از مهمترین آنها گلوتاتیون می‌باشد، بنابراین استفاده از آنتی‌اکسیدان‌ها می‌تواند اثرات ترک مورفین را کاهش دهد. لذا، هدف از مطالعه حاضر بررسی اثر دوزهای مختلف 2-اکسو4-تیازولیدین-کربوکسیلیک اسید (OTC = -2-Oxo-4-Thiazolidine-Carboxylic Acid) (فعال کننده آنزیم گلوتاتیون تراسفراز) بر بیان و کسب وابستگی فیزیکی توسط ...
[ 8 ] - Effects of the stimulation of β2-adrenoceptors of the the basolateral amygdala on anxiety-like behaviors following electrical foot-shock stress in male rat
Introduction: The basolateral amygdala (BLA) is a key structure that integrated anxiety information. It is suggested that baso-lateral area of amygdala receives a dense norepinephrine innervation from the locus coeruleus nucleus. Furthermore, stress increased norepinephrine secretion in the BLA. In the present study, we examined the effects of the stimulation of β2-adrenoceptors in the BLA on a...
[ 9 ] - Cognitive Aspects of COVID-19 Pandemic: The Need of “Pandemiology”
COVID-19 spread rapidly worldwide and became a pandemic disease in April 2020. During this period, various medical complications of this disease have been reported, but less attention has been paid to the cognitive aspects caused by the pandemic. In this review article, an attempt has been made to address the cognitive aspects of COVID-19 disease. Importantly, this disease has caused people to ...
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