Fereshteh Talebpour Amiri
Department of Anatomy, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Zataria multiflora ameliorates cisplatin-induced testicular damage via suppression of oxidative stress and apoptosis in a mice model
Objective(s): Cisplatin (CP), as an anti-neoplastic drug, causes testicular damage. Zataria multiflora Boiss (ZM), a medicinal plant, has antioxidant and anti-inflammatory properties. The aim of this study was to investigate the effects of ZM against CP-induced testicular toxicity. Materials and Methods: In this experimental study, thirty-two adult male mice were randomly divided into four group...
[ 2 ] - 99mTc-Glucarate for assessment of paclitaxel therapy in human ovarian cancer in mice
Objectives: The monitoring of cancer treatment response to chemotherapy is considered an essential strategy for follow-up of patients. The aim of this study was to evaluate the use of 99mTc-glucarate as a radiotracer for in vivo quantification and visualization of necrotic area and therapeutic effect of paclitaxel in ovarian cancer xenografted nude mice. Materials and Methods: After implantatio...
[ 3 ] - اثر محافظتی زنجبیل بر آسیب قلبی ناشی از دیازینون از طریق سرکوب کردن فرایند استرس اکسیداتیو
Background and purpose: Diazinon (DZN), as an organophosphate insecticide, is used in agriculture and have destructive effects on heart. Zingiber officinale (ginger), as a medicinal plant has antioxidant properties. This study was designed to evaluate the effect of ginger against DZN-induced cardiotoxicity in rats. Materials and methods: In this experimental study, 32 adult female Wistar rats ...
[ 4 ] - بررسی اثر سمی نانوذره سریم اکساید بر بیضه موش
Background and purpose: Cerium oxide nanoparticles (CNPs) are widely used as a catalyst in industry and as an antioxidant in applied nanomedicine. The biological effect of CNPs exposure on testis tissue is not known. The objective of this study was to evaluate the effect of CNPs on testis in mice model. Materials and methods: In this experimental study, CNPs were administered intraperitoneally...
[ 5 ] - بررسی اثر محافظتی آتورواستاتین بر کاردیوتوکسیسیتی و سمیت خونی ناشی از سیکلو فسفامید در مدل موش صحرایی
Background and purpose: Cyclophosphamide (CP) is used as an anti-cancer and immunosuppressive agent and it is accompanied with severe cardiotoxicity and anemia. Atorvastatin (ATV) is a widely used medication in hypercholesterolemia that has antioxidant and anti-inflammatory properties at low dose. The aim of this study was to investigate the protective effect of ATV on cyclophosphamide-induced ...
[ 6 ] - بررسی اختلالات عضلانی اسکلتی در پرستاران و ارتباط آن با استرس شغلی
Background and purpose: Musculoskeletal disorders (MSDs) are the most common occupational health problems that have high costs and lead to productivity loss in nurses. On the other hand, work-related stress is another important factor that could result in reduced productivity in organizations and may lead to physical and mental problems in personnel. This study aimed to evaluate the prevalence ...
[ 7 ] - اختلالات اسکلتی عضلانی مرتبط با کار و ارتباط آن با کیفیت زندگی در پرستاران
Introduction: Work-related musculoskeletal disorders (WMSDs) are the most common occupational health problems, reported with high costs and loss of productivity in nurses. On one hand, the quality of life is a multidimensional concept that affects factors such as physical and psychological ones. This study aimed to evaluate the relationship between WMSDs and quality of life in nurses. Method...
[ 8 ] - اثر محافظتی روی (Zn) بر سمیت کبدی ایجاد شده توسط آرسنیک (Ar) در طی دوره جنینی و شیردهی نوزاد موش صحرایی
سابقه و هدف: آرسنیک (Ar) بعنوان یک عامل استرس اکسیداتیو در دوره بارداری و شیردهی می تواند موجب ناهنجاری در نوزاد گردد. از سوی دیگر شواهد حاکی از خاصیت آنتی اکسیدانتی روی (Zn) می باشند. مطالعه حاضر با هدف تعیین اثر محافظتی Zn بر سمیت کبدی ناشی از Ar در طی دوره جنینی و شیردهی نوزاد رت انجام گرفت. مواد و روشها: در این مطالعه تجربی 24 سر رت ماده از بین 35 موش که پس از جفت گیری بارداری آنها تایید ش...
[ 9 ] - رشد و تمایز کندروژنیک سلول های بنیادی مزانشیمی بافت چربی انسانی بر روی داربست کیتوسان
سابقه و هدف: درمان آسیب های غضروفی به هر علتی تنها با کاهش موقت درد مفاصل همراه است. با فراهم آمدن امکان تمایز سلولهای بنیادی از منابع مختلف به بافت های بالغ، می توان به ترمیم و درمان اسیب های وارده به بافتهای غضروفی سیستم اسکلتی امیدوار بود. در این مطالعه، پتانسیل کندروژنیک اسکافولد CH-β-GP-HEC با سلول های بنیادی مشتق از بافت چربی ارزیابی شد. مواد و روشها: در این مطالعه مقطعی سلولهای بنیادی ...
[ 10 ] - Juglans Regia L. Leaf Extract Attenuates Diabetic Nephropathy Progression in Experimental Diabetes: An Immunohistochemical Study
Background: There is accumulating evidence that Juglans regia L. (GRL) leaf extract has hypoglycemic and antioxidative properties. The present study aimed to investigate the protective effects of GRL leaf extract against diabetic nephropathy (DN). Methods: In total, 28 male adult Sprague-Dawley rats were used. The DN rat model was generated by intraperitoneal injection of a single 55 mg/kg dose...
[ 11 ] - Deltamethrin-Induced Hepatotoxicity and Virgin Olive Oil Consumption: An Experimental Study
Background: Deltamethrin (DM) is a synthetic pyrethroid insecticide which can lead to pathological effects in mammals through oxidative stress. On the other hand, virgin olive oil (VOO) is a rich source of phenolic compounds with antioxidants. The aim of the present study was to determine the protective effects of VOO against DM-induced hepatotoxicity. Methods: Thirty-six mice were randomly sep...
[ 12 ] - protective effect of hydro alcoholic extract of Aloysia citriodora against ethanol-induced hepatotoxicity in male Wistar rats via assessment of inflammatory and oxidative stress markers
Objective: Chronic ethanol consumption has significant negative effects on liver tissue. Mechanisms of ethanol toxicity include oxidative stress and inflammation. The antioxidant and anti-inflammatory properties of the lemon verbena have been proven in studies. The aim of this study was to evaluate the protective effect of hydro alcoholic extract of Aloysia citriodora (AC) on ethanol-induced he...
[ 13 ] - Effects of Moderate Treadmill Exercise and Fluoxetine on Spatial Memory, Anxiety, and Positive Tunnel Cells in the Hippocampus in a Rat Model of PTSD
Background and purpose: Post-traumatic stress disorder (PTSD) is a condition that develops after experiencing major trauma. Selective serotonin reuptake inhibitors (SSRIs) are first-line treatment for PTSD. This study aimed at investigating the effects of moderate treadmill exercise and fluoxetine on anxiety, spatial memory, and positive tunnel cells in the hippocampus in a rat model of PTSD. ...
[ 14 ] - Effect of Lipogel Containing Extracts of Eryngium campestre L. and Satureja hortensis L. on Wound Healing in Male Wistar Rats
Background and purpose: Wound is a type of injury with high prevalence in the society. The main requirement for wound management is rapid and complete wound healing without the spread of infection. Medicinal plants are affordable and accessible and suggested as one of the key treatment options. The aim of this study was to investigate the effect of lipogel formulations containing the extract...
[ 15 ] - The relationship between Osteoarthritis and Osteoporosis in the Relationship between Osteoarthritis and Osteoporosis in A Population of Patients Attending Sari Hospitals
Background and purpose: Osteoarthritis and osteoporosis are the most important causes of skeletal disorders and there are controversies over the relationship between these diseases and other factors. The aim of the present study was to investigate the relationship between osteoarthritis and osteoporosis and also the association between these two diseases and patients’ demographic and lifestyle...
[ 16 ] - Correction to: The Relationship between Osteoarthritis and Osteoporosis in A Population of Patients Attending Sari Hospitals
Correction to: The Relationship between Osteoarthritis and Osteoporosis in A Population of Patients Attending Sari Hospitals Davood Nasiry1, Masood Shayesteh Azar2, Samira Andarkhora3, Fereshteh Talebpour Amiri4 1 Assistant Professor, Department of Anatomy, Amol Faculty of Paramedicine, Mazandaran University of Medical Sciences, Sari, Iran 2 Associate Professor, Department of Ortho...
[ 17 ] - Protective Effect of Atorvastatin on Benzopyrene-Induced Hepatorenal Toxicity: A Histopathological Study
Background and purpose: Benzo[a]pyrene (BaP) is an environmental pollutant that has genotoxic and carcinogenic effects. Atorvastatin (ATV), as a lipid-lowering drug, has antioxidant, anti-inflammatory and anti-apoptotic properties. This study investigated the effects of ATV on chronic liver and kidney damage induced by BaP. Materials and methods: In this experimental study, adult female rats w...
[ 18 ] - Beneficial effects of Pimpinella anisum L. ethanol and aqueous extracts on L-asparaginase-associated hepatotoxicity using specific 99mTc-Phytate biodistribution studies in rats
Introduction: The present study aimed to investigate the protective effects of Pimpinella anisum L. ethanolic and aqueous extracts on L-asparaginase- associated hepatotoxicity in rats using histopathological and specific 99mTc-Phytate biodistribution studies. Materials and Methods: 60 female rats were divided into 9 treatment groups including L-asparaginase group, Aqueous extract (100 and 200 m...
[ 19 ] - Comparing the Effect of Treadmill Exercise and Fluoxetine on Sex Hormones, Testicular Histopathology, and Fear Extinction in Adult Wistar Rats with Post-Traumatic Stress Disorder
Background and purpose: Post-traumatic stress disorder (PTSD) is a mental and physical complication. Fluoxetine (FLX) as a selective serotonin reuptake inhibitor is considered as the first line of treatment for PTSD. Exercise can improve the symptoms of PTSD. The aim of this study was to determine the effects of exercise and FLX on testicular tissue and sex hormones in rats with PTSD. Materia...
[ 20 ] - Curcumin Ameliorates Sodium Valproate Induced Neurotoxicity through Suppressing Oxidative Stress and Preventing Mitochondrial Impairments
Background and purpose: Curcumin is a natural polyphenolic compound in turmeric (Curcuma longa). Curcumin has potent free radical scavenger and antioxidant properties that could significantly reduce oxidative damage. Oxidative stress and mitochondrial dysfunction contribute to valproate sodium induced tissue damage. This study investigated the protective effects of curcumin against valproate so...
[ 21 ] - A Review of Applications of Nanoceria in Cancer
Cancer is one of the most difficult diseases to treat in modern medicine. Annually, many articles are published that propose various ways for preventing carcinogenesis. Furthermore, research into cancer treatments is carried out with minimal side effects. The most common non-invasive cancer treatments include chemotherapy, targeted therapy, radiotherapy, and immunotherapy. Low effectiveness of...
[ 22 ] - Evaluating the Effect of Lipogel Formula Containing Extracts of Rhamnus cathartica L. on Wound Healing in Wistar Rats
Background and purpose: Wound is a complication that is highly prevalent. The aim of this study was to investigate the effect of a lipogel formulation containing Rhamnus cathartica L., a native Iranian plant, on wound healing in Wistar rats. Materials and methods: In this experimental study, to find the best lipogel formula, several formulations with different ratios of paraffin, polyethylene ...
[ 23 ] - The effect of a topical ointment containing methanol extract of Buxus hyrcana Pojark. leaves on cutaneous wound healing in rats
Introduction: Buxus hyrcana Pojark. has been traditionally used for the treatment of skin disorders including wound injuries and recent studies have shown the therapeutic potential of some Buxus species in healing skin wounds. In this study, the effect of an ointment containing methanolic extract of B. hyrcana leaves was evaluated on the full-thickness wound healing in a rat model. Materials an...
[ 24 ] - Responsiveness to the Effect of Fluoxetine in Male and Female Rats Exposed to Single Prolonged Stress: A Behavioral, Biochemical, Molecular and Histological Study
Background: Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine are the first-line choice in patients with PTSD. Animal studies have indicated that chronic fluoxetine exposure leads to persistent behavioral changes and neuroplasticity in the hippocampal formation and cortex. Previous studies revealed that adult female rats respond differently to trauma from adult males. Here, we hav...
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