Amin Tamadon
Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
[ 1 ] - Spermatogenesis after transplantation of adipose tissue-derived mesenchymal stem cells in busulfan-induced azoospermic hamster
Objective(s): Adipose tissue-derived mesenchymal stem cells (AT-MSCs) with more potent immunomodulatory effects, greater proliferative potential and secretion of growth factors and cytokines in comparison with bone marrow derived MSCs are more appropriate for cell therapy. The aims of the present study were to evaluate the histomorphometric effect of AT-MSCs allotransplantation on regeneration ...
[ 2 ] - Intrauterine xenotransplantation of human Wharton jelly-derived mesenchymal stem cells into the liver of rabbit fetuses: A preliminary study for in vivo expression of the human liver genes
Objective(s): End-stage hepatic failure is a potentially life-threatening condition for which orthotopic liver transplantation is the only effective treatment. However, a shortage of available donor organs for transplantation each year results in the death of many patients waiting for liver transplantation. Xenotransplantation, or the transplantation of cells, tissues, or organs between differe...
[ 3 ] - Expression of melanocortin-4 receptor and agouti-related peptide mRNAs in arcuate nucleus during long term malnutrition of female ovariectomized rats
Objective: Melanocortin-4 receptor (MC4R) and agouti-related peptide (AgRP) are involved in energy homeostasis in the rat. The aim of the present study was to evaluate the expression of MC4R and AgRP mRNAs in arcuate nucleus (ARC) during long term malnutrition of female ovariectomized rats. Materials and Methods: Ten female ovariectomized rats were divided into two equal groups (n=6) of normal ...
[ 4 ] - Increased litter size and suckling intensity inhibit KiSS-1 mRNA expression in rat arcuate nucleus
Objective(s): The effect of litter size and suckling intensity on the expression of KiSS-1 mRNA in the arcuate nucleus (ARC) of rats were evaluated. Materials and Methods: Thirty two pregnant and four non-lactating ovariectomized (as control group) rats were used in this experiment. Lactating rats were allotted to eight equal groups. In three groups, litter size was adjusted to 5, 10, or 15 pup...
[ 5 ] - Busulfan induced azoospermia: Stereological evaluation of testes in rat
The aim of the present study was stereological evaluation of testes of azoospermic animal model using busulfan in rat. Three groups of male adult rats were used in this study. The first group was injected by single dose of busulfan (10 mg kg-1) and their testes were removed on day 35 post injection. The second group received double doses of busulfan with 21 days interval and their te...
[ 6 ] - Histomorphometric study of brachiocephalic artery of Japanese quail
Brachiocephalic arteries in quails are large arteries which are arising separately from the aortic arch. The aim of the present study was to determine the histomorphometric aspects of brachiocephalic arteries in the Japanese quail. The different layers of the brachiocephalic artery were studied quantitatively in 10, 20 and 60 days-old Japanese quail; (n = 6) and both sexes. Luminal diameter, th...
[ 7 ] - Histomorphometric changes of small intestine in pregnant rat
Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 of pregnancy) were collected. Villous height a...
[ 8 ] - Luteal activity of Abadeh ecotype does in summer and winter and the effect of a single dose of kisspeptin-10 injection on luteinizing hormone secretion in the anestrus does
The aims of the present study were to evaluate luteal activity in Abadeh ecotype goat during summer and winter and also the effect of a single dose kisspeptin-10 injection on the secretion of luteinizing hormone (LH) in female anestrous goats. In the first study, progesterone (P4) concentration in 10 goats in summer (n = 6) and winter (n = 4) were measured every other day. Moreover, ...
[ 9 ] - Relationship between season, lactation number and incidence of clinical mastitis in different stages of lactation in a Holstein dairy farm
The aim of the present study was to compare the occurrence and duration of clinical mastitis in different seasons, stages of lactation period and parities in a Holstein dairy farm in Iran. A retrospective epidemiological survey from April 2005 to March 2008 was conducted on 884 clinical mastitis cases of 7437 lactations. Data of each case including calendar-date of mastitis onset, days in milk ...
[ 10 ] - ویژگی های تولید مثلی گوزن زرد ایرانی (Dama dama mesopotamica) در پناهگاه حیات وحش دشت ناز ساری
گوزن زرد ایرانی (Dama dama mesopotamica) نشخوارکننده‌ای از خانواده گوزن‌سانان است. در حال حاضر در ایران جمعیت‌‌هایی از گوزن زرد ایرانی در مازندران، خوزستان و آذربایجان غربی تحت مراقبت هستند. نگهداری و حفاظت از گوزن زرد ایرانی نیازمند شناخت خصوصیات رفتاری، فیزیولوژی، محیط و عوامل آسیب رسان به این گونه می‌باشد. تاکنون اطلاعات طبقه‌‌بندی شده‌ای از برخی خصوصیات گوزن زرد ایرانی شامل رفتارشن...
[ 11 ] - تغییر نسبت جنسی نوزادان موش صحرایی در پاسخ به مکمل پتاسیم جیره
زمینه مطالعه: برخی یون‌های جیره می‌توانند با اثر بر دستگاه تولیدمثل ماده یا لایه‌های اطراف اووسیت، نفوذ اسپرم با نوع خاصی کروموزوم را تسهیل کنند و نسبت جنسی نوزاد پستانداران را تغییر دهند. هدف: بررسی اثر مکمل پتاسیم بر تغییر نسبت جنسی نوزادان موش‌های صحرایی. روش‌کار: درصد رطوبت، خاکستر، چربی و پروتین خام، سدیم، پتاسیم، کلسیم و انرژی جیره موش‌های صحرایی اندازه‌گیری شد. در گروه شاهد نوزادان نر و...
[ 12 ] - Expression of Melanocortin 4 Receptor mRNA in Male Rat Hypothalamus During Chronic Stress
The effects of chronic stress and glucocorticoids receptor antagonist (RU486) on expression of melanocortin 4 receptor (MC4R) mRNA in arcuate nucleus (ARC) of male rats were evaluated. In this study, adult male Sprague Dawley rats were placed into four groups (n=6/group) stress, RU486, stress/RU486, and control groups. In stress group, the rats were restrained, 1 h/day, for 12 days. In RU486 gr...
[ 13 ] - Hypothalamic Expression of Melanocortin-4 Receptor and Agouti-related Peptide mRNAs During the Estrous Cycle of Rats
Melanocortin- 4 receptor (MC4R) and agouti- related peptide (AgRP) are involved in energy homeostasis in rats. According to MC4R and AgRP effects on luteinizing hormone (LH) secretion, they may influence the estrous cycle of rats. Therefore, the aim of this study was to investigate the expression of MC4R and AgRP mRNAs at different stages of estrous cycle in the rat’s hypothalamus. The estrous ...
[ 14 ] - Mechanical activity of isolated aorta strips after prolonged exposure to low frequency electromagnetic fields and its interaction with the cholinergic and adrenergic systems in male rat
Introduction: Public concern about the potential effects of electromagnetic field (EMF) on human health is increased by progressive usage of electrical devices in modern life. The aim of this study was to investigate the effect of prolonged exposure to low frequency EMF on the mechanical activity of isolated thoracic aorta strips in rats. Methods: Fourteen male rats were randomly allocated into...
[ 15 ] - Pathophysiological mechanisms of gonadotropins– and steroid hormones–related genes in etiology of polycystic ovary syndrome
Objective(s): Polycystic ovary syndrome (PCOS) is an endocrinopathy in women, which, unlike its impact on fertility and health of women, there is no clear understanding about the causal mechanisms of this pathogenesis. The aim of this review paper is to investigate the pathophysiological pathways affecting the PCOS etiology, based on functions of gonadotropins– and steroid hormones–related gene...
[ 16 ] - The roles of RFamide-related peptides (RFRPs), mammalian gonadotropin-inhibitory hormone (GnIH) orthologues in female reproduction
Objective(s): To benefit from reproduction and deal with challenges in the environmental conditions, animals must adapt internal physiology to maximize the reproduction rate. Maladaptive variations in the neurochemical systems and reproductive system can lead to manifestation of several significant mammalian reprocesses, including mammalian ovarian lifespan. RFamide-related peptide (RFRP, Rfrp)...
[ 17 ] - Regenerative Effect of Bone Marrow-derived Mesenchymal Stem Cells in Thioacetamide-induced Liver Fibrosis of Rats
The present study determined the regenerative effect of bone marrow-derived stem cells (BMSCs) on thioacetamide (TA)-induced liver fibrosis in rats. A total of 30 male Wistar rats were randomly divided into sham control and treatment groups. The rats of the sham control group were subdivided into three groups and sampled on the 14th, 18th, and 20th weeks after fibrosis induction. The rats of th...
[ 18 ] - Pathophysiologic mechanisms of obesity- and chronic inflammation-related genes in etiology of polycystic ovary syndrome
Objective(s): One of the common heterogeneous reproductive disorders in women of childbearing age is polycystic ovary syndrome (PCOS). It is characterized by lack of fertility due to anovulatory cycles, hyperandrogenemia, polycystic ovaries, hyperinsulinemia, and obesity. Both reproductive anomalies and metabolic disorders are involved in PCOS pathology. Although the r...
[ 19 ] - Growth Kinetics, Characterization, and Plasticity of Human Menstrual Blood Stem Cells
One of the readily available sources of mesenchymal stem cells (MSCs) is menstrual blood-derived stem cells (Men-SCs), which exhibit characteristics similar to other types of MSCs. This study was performed to determine the growth kinetics, plasticity, and characterization of Men-SCs in women. During spring 2014 in the southern Iranian city of Shiraz, menstrual blood (5 mL) was obtained from 10 ...
[ 20 ] - Low-power Density Radiations Emitted from Common Wi-Fi Routers Influence Sperm Concentration and Sperm Histomorphometric Parameters: A New Horizon on Male Infertility Treatment
Background: Male infertility is defined as an inability to impregnate a fertile female; it is a widespread problem which is usually caused by some male factors such as low quantity and quality of sperm, specifically oligospermia and azoospermia. Objective: This study aimed to evaluate the bio-positive effects of low power density Wi-Fi radiation on the reproductive system of infertile and...
[ 21 ] - Decreased Expression of Arginine-Phenylalanine-Amide-Related Peptide-3 Gene in Dorsomedial Hypothalamic Nucleus of Constant Light Exposure Model of Polycystic Ovarian Syndrome
Objective An abnormality in pulse amplitude and frequency of gonadotropin releasing hormone (GnRH) secretion is the most characteristics of polycystic ovarian syndrome (PCOS). On the other hand, arginine-phenylalanine-amide (RFamide)-related peptide-3 (RFRP3) inhibits the secretion of GnRH in mammalian hypothalamus. Therefore, the current study evaluated the expression of RFRP3 mRNA in dorsomed...
[ 22 ] - The Role of Arginine-Phenylalanine-Amide-Related Peptides in Mammalian Reproduction
Until 2000 it was believed that gonadotropin-releasing hormone (GnRH) was the sole regulator of hypophyseal gonadotropes. In 2000, the discovery of a gonadotropin inhibitory hormone (GnIH) initiated a revolution in the field of reproductive physiology. Identification of GnIH homologues in mammals, the arginine-phenylalanine- amide (RFamide)-related peptides (RFRPs), indicated a similar function...
[ 23 ] - Increased Litter Size and Suckling Intensity Stimulate mRNA of RFamide-related Peptide in Rats
Background RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial hypothalamic nucleus (DMH) of rats. MaterialsAndMethods A total of 32 pregnant and 4 non-lactating ovariectomized (control group) Sprague-Dawl...
[ 24 ] - Conocarpus Tree the Marine-Medicinal Treasure of Southern Iran: A Review of Botani-cal, Phytochemical and Medicinal Properties
Conocarpus is a tree with two flowering species of Conocarpus lancifolius and Conocarpus erectus. It is commonly known as, it is commonly known as sycamore tree or white buttonwood mangrove in Iran. It durable and can withstand conditions such as extremely high temperatures, low drainage, pressurized soil, air pollution, and salty water. In the past, this tree was used to treat various diseases...
[ 25 ] - Enki or Ea: The god of medicine in Mesopotamia from the sea
Enki or Ea. is the name of the god of wisdom, medicine and sea in the Mesopotamia Sumer and Elam. He is the ruler of the freshwater ocean, “Abzu”. Enki is represented by the rivers Euphrates and Tigris flowing from his shoulders. He has a bowl in his hand from which water flows. He is associated with his symbolic animals such as fish, goats and turtles. Boats and canes with ram heads are his to...
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