Roghayeh Abbasalipourkabir
Department of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
[ 1 ] - Effects of insulin-loaded chitosan-alginate nanoparticle on RAGE expression and oxidative stress status in the kidney tissue of rats with type 1 diabetes
Objective(s): Chronic hyperglycemia leads to activation of the advanced glycation end products (AGE)-receptor (RAGE) for AGE axis and oxidative stress, which promote diabetic renal damage. This study examines the effect of insulin-loaded trimethyl chitosan nanoparticles on the kidney tissue of diabetic rats. Materials and Methods: Twenty-five male Wistar rats were randomly divided into 5 groups...
[ 2 ] - STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L.) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH STZ
Background & Aims: The aim of this study was to evaluate the protective effects of raspberry fruit extract (Rubus fruticosus L.) on LH, FSH, testosterone serum levels, and number and percentage of sperm motility in male diabetic rats induced with streptozotocin. Materials & Methods: In this experimental study, 50 Wistar male rats were used and divided into five groups: (control), diabetic (STZ...
[ 3 ] - Investigating Anticancer Effects of Silver Nanoparticles on Bladder Cancer 5637 Cells in Comparison to Human Embryonic Kidney Normal Cells (HEK-293)
Background & aim: Nanotechnology is a modern research field with broad applications in cancer management. Among the various metal nanoparticles, silver nanoparticles (AgNPs) have been used in cancer therapy due to their promising anti-tumor properties. Despite the great advantages of AgNPs, their effects on normal cells have become a challenge. Besides, their anti-cancer effects have not previo...
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