S. Saraswat

Department of Physiology Reproduction and Shelter Management, Central Institute for Research on Goats, Mathura, India

[ 1 ] - Estrogens Receptors-New Players in Spermatogenesis

The mammalian testis is a complex organ that serves two important functions, synthesis of steroids, with significant amount of estrogenic hormones produced and production of spermatozoa. Estrogen receptors (ERs) are expressed in cells of the testis as well as the epididymal epithelium. We have demonstrated that estrogen receptor expression is higher in reproductive tissues as compared to non-re...

[ 2 ] - Impact of Reactive Oxygen Species on Spermatozoa: ABalancing Act between Beneficial and Detrimental Effects

Reactive oxygen species (ROS)plays an important role in sperm motility. The physiological generation at low concentration induces beneficial effects on sperm functions and plays a significant role in sperm metabolism. Meanwhile, the excessive generation of reactive oxygen species can overwhelm protective mechanism and triggers changes in lipid and protein layers of sperm plasma membrane, which ...

[ 3 ] - Estrogen receptor gene 1 expression in caprine and its effect on fertility

The present study was undertaken to analyze the expression pattern of estrogen receptor 1 gene (ESR1) in Barbari bucks (fertile and non-fertile) identified on the basis of seminal quality traits and fertility trials. RNA was extracted from the spleen by Trizol method. The expression pattern of ESR1 gene was analyzed using real time polymerase chain reaction (RT-PCR). The expression pattern of E...

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