Mohammad Sadegh Rezai
Associate Professor, Research Center with Focus on Nosocomial Infection, Bouali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - The Effect of Video Game Play Technique on Pain of Venipuncture in Children
Background The present study was designed and conducted to determine the effect of video game play on pain of venipuncture in 3-6 year-old children. Materials and Methods This randomized controlled trial study was conducted on 80 hospitalized children with pain of venipuncture procedures. Playing a video computer game for children during the venipuncture procedures was the intervention for the ...
[ 2 ] - The Effect of Distraction Technique on the Pain of Dressing Change among 3-6 Year-old Children
Background Burn dressings, debridement, surgical incisions, skin grafting and physical therapy are some of painful treatments of burn. According to the studies, distraction techniques have a significant effect on patients’ pain. The present study was designed and conducted to determine the effect of distraction on pain of dressing change in second degree burn in 3-6 year-old children. Materials...
[ 3 ] - مقایسه اثر درمان آزیترومایسین، آموکسی سیلین و کو- آموکسی کلاو در درمان کودکان مبتلا به سینوزیت باکتریایی حاد: یک مطالعه کارآزمایی بالینی تصادفی شده
Background and purpose: Acute bacterial sinusitis is a very common disease among children. Empirical therapy for acute bacterial sinusitis often includes a 10-14-day period of β-lactamase. Azithromycin, a sustained high tissue level macrolide, due to its pharmacokinetic profile can be used once daily in a shorter treatment course of 3 to 5 days. This study aimed to compare azithromycin and comm...
[ 4 ] - فراوانی کم کاری تیروئید در بیماران دیابتی نوع یک زیر 16 سال
Background and purpose: Diabetes mellitus is the most common endocrinologic disease in children and adolescents. Type 1 diabetes mellitus (T1DM) is frequently associated with autoimmune thyroid disease. It is believed that the prevalence of thyroid disease in T1DM patients is higher than normal population. Various studies reported the incidence of hypothyroidism as 2-32% in T1DM. This study inv...
[ 5 ] - اثر بخشی و عوارض شیره ریشه اکیناسه در درمان سرماخوردگی کودکان: یک مطالعه کارآزمایی بالینی تصادفی شده
Background and purpose: Common cold is the most prevalent viral infection in children that is associated with high health care expenditure every year. Echinacea is commonly used to prevent viral respiratory infections. The goal of this study was to assess Echinacea effect in improving the symptoms of acute upper respiratory tract infection (URI) in children. Materials and methods: This clinica...
[ 6 ] - بررسی فراوانی سکانس باکتریال در بیماران کاوازاکی بستری درمرکز طبی کودکان به روش Universal PCR طی سال های 86-85
Background and Purpose: The clinical and epidemiologic features of Kawasaki disease (KD) suggest an infectious etiology however, the agent(s) remain unknown. Our purpose was to isolate the causative bacterial gene from peripheral blood leukocytes of patients with acute KD, by Universal polymerase chain reaction (UPCR), in Tehran Children’s Medical Center. Materials and Methods: Universal p...
[ 7 ] - Conjugate and 23-valent pneumococcal polysaccharide booster vaccination in asplenic patients with thalassemia major: A randomized clinical trial study
Background: Pneumococcal vaccine provides protection against invasive pneumococcal disease in population at risk. This study was conducted to compare the antibody response to 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine in patients with thalassemia major. Methods: A randomized cross-over clinical trial was performed on 50 asplenic patients with t...
[ 8 ] - Multidrug resistance pattern of bacterial agents isolated from patient with chronic sinusitis
Background: Treatment of chronic sinusitis is complicated due to increase of antibiotic-resistant bacteria. The aim of this study was to determine the multidrug resistance (MDR) pattern of the bacteria causing chronic sinusitis in north of Iran. Methods: This cross-sectional study was carried out on patients with chronic sinusitis. Bacterial susceptibility to antimicrobial agents was determi...
[ 9 ] - Efficacy of probiotic use in acute rotavirus diarrhea in children: A systematic review and meta-analysis
Background: Probiotic therapies with different strains demonstrated some beneficial effects, although some studies did not show any significant effects. This study assessed systematically the current knowledge on the effect of probiotic bacteria on duration of in acute rotavirus diarrhea in children compared with control. Methods: The PubMed, Cochrane Controlled Trial Register (CCTR) and Ov...
[ 10 ] - Ultra structural characteristics of methicillin resistant Staphylococcus aureus cell wall after affecting with lytic bacteriophages using atomic force microscopy
Objective(s): During the last years with increasing resistant bacteria to the most antibiotics bacteriophages are suggested as appropriate treatment option. To investigate lytic activity of bacteriophages there are indirect microbial procedures and direct methods. The present study to complement microbial procedures and investigate ultra-structural characteristics of infection bacterium-phage u...
[ 11 ] - ضایعات ناخن در کودکان مبتلا به بیماری دست، پا و دهان
Background and Aim: Hand, foot, and mouth disease (HFMD) is a common contagious infectious disease. Because of the current limited knowledge about the etiology of this disease and its associated complications, especially nails lesions, we conducted this study to determine the prevalence of the nail disorders in children with HFMD. Methods: In this cross-sectional study, 84 children whom were...
[ 12 ] - بررسی فراوانی عفونت ادراری در نوزادان با هایپر بیلی روبینمی
Background and purpose: Hyperbilirubinemia is the most common cause of neonatal hospitalization and can be a sign of urinary tract infection during infancy. Urinary tract infection (UTI) is one of the reasons for prolonged jaundice. This research aimed at studying the prevalence of urinary tract infection in neonates with hyperbilirubinemia admitted to Tonekabon Shahid Rajaei Hospital, 2015. M...
[ 13 ] - فاژ درمانی در عفونت های ناشی از باکتری های گرم منفی
Background and purpose: Infections caused by multidrug-resistant gram-negative bacteria are rising. Phage therapy is an effective treatment in infections resistant to treatment and progress has been made with its use and development in recent years. Phage therapy in treatment of gram-negative bacterial infections is not well investigated in clinical trials. Therefore, the aim of this study was ...
[ 14 ] - Epiglottitis in Pre and Post Haemophilus Influenza Type-b Vaccine Era: A Systematic Review and Meta-analysis
Background and purpose: Epiglottitis is an uncommon life threatening pediatric disease. Evidence suggests some changes in etiology and incidence of this disease after vaccination against H-influenza type b. This Meta-analysis and systematic review aimed at investigating the etiology and incidence of acute epiglottitis in pre and post H-influenza vaccination era. Materials and methods: A system...
[ 15 ] - Intralesional Injection of the Measles–Mumps–Rubella Vaccine into Resistant Palmoplantar Warts: A Randomized Controlled Trial
Background: Common resistant-to-therapy warts pose a challenge to both clinicians and patients. Among many destructive and immunotherapeutic options, no single, fully effective treatment has been suggested yet. Many investigations, including those using intralesional antigen administrations, have demonstrated that cellular immunity plays a major role in the clearance of human papilloma virus (H...
[ 16 ] - Total delay and associated factors in pulmonary tuberculosis patients in Golestan province
Background: Delay in diagnosis and treatment of TB is a critical component in TB control program which thereby spreading illness in the community. Sicnce Golestan province has the high risk with high rates of tuberculosis in the country, therefore, the analysis of the factors associated with treatment delay in this province for effective interventions and proper planning is considered necessary...
[ 17 ] - Invasive and Non-invasive Mechanical Ventilation in Pediatric Patients with COVID-19: A Systematic Review
Background and purpose: In the last months of 2019, the new coronavirus infection (COVID-19) spread worldwide. This study investigated the need for mechanical ventilation in children who were admitted for COVID-19. Materials and methods: This article provides a systematic review of studies about children with COVID-19 requiring invasive or non-invasive mechanical ventilation. Electronic databa...
[ 18 ] - Diagnosis of Sepsis in Children Using the BACTEC Method
Background and purpose: Sepsis is a bacterial infection. Many patients lose their lives due to delayed diagnosis. The BACTEC method could be used for rapid and precise diagnosis of sepsis which can isolate different organisms in the shortest time with maximum sensitivity. This study aimed to identify the prevalence of positive blood cultures using the BACTEC in children with sepsis and to deter...
[ 19 ] - Admission Rate and Factors Associated with COVID-19 Disease in Children Attending the Emergency Department in Hospitals Affiliated to Mazandaran University of Medical Sciences, 2019-2020
Background and purpose: Coronavirus (COVID-19) in children includes 1 to 5% of all cases but child mortality due to the disease is rare. The aim of this study was to determine the admission rate and factors associated with Covid-19 disease in children to better understand and control the disease. Materials and methods: In a descriptive-analytical and cross-sectional study 594 samples were se...
[ 20 ] - Epidemiological and Clinical Characteristics of Kawasaki Disease in Mazandaran
Background and purpose: Kawasaki is an acute childhood vasculitis of unknown cause that if left untreated can cause coronary aneurysms in 25% of cases. The disease is reported as the leading cause of acquired heart disease in children in developed countries. The purpose of this study was to investigate the epidemiological and clinical features of Kawasaki disease in northern Iran. Materials an...
[ 21 ] - Gastrointestinal Features of the Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19 Infection in Selected Referral Hospitals in Iran
Background and purpose: Multisystem Inflammatory Syndrome in Children (MIS-C) occurs after having COVID-19. The severity and outcomes of COVID-19 with gastrointestinal symptoms are higher. The aim of this study was to investigate gastrointestinal manifestations in MIS-C patients in selected referral hospitals in Iran to obtain comprehensive information about the treatment and prevention of MIS...
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