Karimollah Hajian
Dept of Biostatistics and Epidemiology, Babol University of Medical Sciences, Babol, IR Iran.
[ 1 ] - The Effect of Oral Zinc Sulfate on Serum Bilirubine Level in Term Neonates with Jaundice
Background The most commonly used treatment for neonatal hyperbilirubinemia (NH) are phototherapy and exchange transfusion. Among the drug therapy for NH less has been paid to the effect of zinc administration on serum bilirubin level (SBL). This study was carried out to determine the on the effect of oral zinc sulfate on the SBL in term neonates with hyperbilirubinemia. Materials and Methods I...
[ 2 ] - بررسی همهگیری شناختی اعتیاد در معتادان خودمعرف مراجعهکننده به مراکز ترک اعتیاد
مقدمه: شیوع بالای اعتیاد عوارض جسمی و روحی- روانی زیادی را به جامعه تحمیل میکند بهطوریکه از نظر بهداشت، مصرف مواد مخدر تزریقی یکی از راههای اصلی انتقال ایدز در کشور ما است و از نظر اجتماعی بیشتر زندانیان کشور در رابطه با جرائم مرتبط با مواد مخدر مجرم شناخته شدهاند. بنابراین، شناخت عوامل دموگرافی، اجتماعی و فرهنگی در گرایش به اعتیاد، پیشگیری و شناخت همهگیری آن اهمیت ویژهای دارد. هدف: هم...
[ 3 ] - شیوع ناهنجاریهای عمده ظاهری و برخی از عوامل مرتبط با آن درنوزادان متولد شده در زایشگاه بیمارستان شهید یحیینژاد بابل (1380)
چکیده مقدمه: امروزه ناهنجاری های مادرزادی یک علت شایع ناتوانی طولانی مدت و مرگ و میر کودکان را تشکیلمیدهد و این ناهنجاریها بخش مهمی از مشکلات پزشکی میباشد. هدف: این مطالعه به منظور تعیین شیوع ناهنجاریهای عمدهآشکار در نوزادان متولد شده در زایشگاه شهیدیحیینژاد بابل انجام شده است. مواد و روشها: این مطالعه مقطعی بروی 3756 پرونده بیمارستانی نوزادان ب...
[ 4 ] - بررسی فاصله گذاری بین تولدها و عوامل مرتبط با آن در مادران چندم زای مراجعه کننده به زایشگاه ها و مراکز بهداشتی درمانی شهری بابل (1386)
Background and purpose: Birth spacing has become a main strategy within health promotion programs for mothers and their children during the past two recent decades in the Islamic Republic of Iran. The present study was aimed to determine the patterns and factors associated with birth intervals in Multi-Para women residing in Babol. Materials and methods: We conducted a cross-sectional stu...
[ 5 ] - فراوانی رفتارهای پرخطر سلامتی در دانشجویان دانشگاههای بابل طی سال 1388
زمینه و هدف : نوجوانان و جوانان از یک طرف عامل اصلی پیشرفت و اعتلای جامعه میباشند و از طرفی به عنوان گروه اصلی در معرض خطر مسائل رفتاری هستند. این مطالعه به منظور تعیین میزان شیوع رفتارهای پرخطر در دانشجویان دانشگاههای بابل انجام گرفت. روش بررسی : این مطالعه توصیفی مقطعی روی 882 دانشجوی دانشگاههای بابل با اجرای نمونهگیری ترکیبی در سال 1388 انجام گرفت. اطلاعات مورد نظر از طریق پرسشنامه مدون...
[ 6 ] - روند تغییرات هفت ساله در الگوی انتخاب روش های پیشگیری از بارداری در جمعیت روستایی بابل (79-1373)
مقدمه و هدف: میزان استفاده از روش های پیشگیری از بارداری یکی از معیارهای مهم در ارزشیابی عملکرد زنان واجد شرایط نسبت به برنامه تنظیم خانواده می باشد. این مطالعه با هدف مقایسه الگوی تغییرات هفت ساله در استفاده از روش های پیشگیری از بارداری در جمعیت روستایی بابل می باشد. مواد و روش ها: این مطالعه بر اساس اطلاعات موجود از پرونده و دفاتر تنظیم خانواده طی سال های 79-1373 و با نمونه ای از 400 نفر از ...
[ 7 ] - بررسی اپیدمیولوژیک بیماران مبتلا به سرطان مری در مراجعه کنندگان به مرکز پرتو درمانی شهید رجایی بابلسر (77-1371)
زمینه و هدف: نواحی شمالی ایران در کرانه جنوبی دریای خزر بر روی کمربند آسیایی سرطان مری قرار دارد که دارای بالاترین میزان بروز سرطان مری در آمارهای جهانی است. هدف از این بررس تعیین مشخصه های اپیدمیولوژیک بیماران مبتلا به سرطان مری در نقاطی از شمال ایران می باشد.مواد و روشها: این مطالعه براساس اطلاعات موجود از پرونده 668 نفر از بیماران مبتلا به سرطان مری مراجعه کننده به مرکز پرتودرمانی شهید رجایی...
[ 8 ] - شیوع چاقی شکمی در جمعیت شهری 20 تا 70 ساله استان مازندران(سال 1383)
مقدمه: چاقی شکمی (مرکزی) از پیامدهای ناشی از تغییر در رفتارها و شیوهی زندگی است. این مطالعه با هدف تعیین الگوی شیوع چاقی شکمی و برخی عوامل مرتبط در جمعیت شهری 20 تا 70 ساله استان مازندران انجام شد. مواد و روشها: این پژوهش به روش مقطعی و مبتنی بر جمعیت بود و با نمونهای از 3600 نفر از طریق نمونهگیری تصادفی خوشهای در جمعیت شهری استان مازندران در سال1383 انجام شد. اندازههای تنسنجی (قد، وز...
[ 9 ] - Comparative evaluation of the frequency of myofibroblasts between oral and cutaneous squamous cell carcinomas
Introduction: Differentiation of fibroblasts to myofibroblasts is an initial and very important event in tumor genesis. Myofibroblasts produce proteinases that stimulate invasion in cancers. Due to the more malignant potential of oral squamous cell carcinoma (OSCC) compared to cutaneous squamous cell carcinoma (CSCC) , the aim of the present study was to compare myofibroblasts between OSCC and ...
[ 10 ] - Cytomegalovirus infection and risk of preeclampsia: A meta-analysis of observational studies
Background: Cytomegalovirus (CMV) infection is one of the most common infectious diseases in pregnant women in terms of global impact and is related with many adverse health consequences during pregnancy. For the first time, we performed a systematic review and meta-analysis study to evaluate the possible association between CMV infection and preeclampsia (PE). Methods: A comprehensive literat...
[ 11 ] - Metabolic syndrome and different obesity phenotypes in the elderly women population: Iran’s Health System on aging
Background: Current literature has been focused on types of obesity with normal BMI (body mass index), but metabolically unhealthy.This study evaluates the prevalence of metabolical phenotypes of obesity. We also identified the best obesity index in predicting the components of metabolic syndrome (MetS). Methods: A cross-sectional study has been conducted on 164 women over 60 years. Anthropome...
[ 12 ] - Effect of long-term low dose prednisolone administration on bone mineral density: Relating to non-compliant women with rheumatoid arthritis
Background: Long-term treatment of rheumatoid arthritis (RA) with prednisolone (PRED) is associated with bone mineral density (BMD) loss. This study aimed to determine the status of BMD in non-compliant women who used PRED alone for RA. Methods: Non-adherent RA taking < 7.5 mg daily PRED without DMARDs for > 6 months, and RA patients taking methotrexate +PRED (RA control) were compared with ag...
[ 13 ] - Analgesic effects of lidocaine-ketorolac compared to lidocaine alone for intravenous regional anesthesia
Background: Intravenous regional anesthesia is a simple and reliable method for upper extremity surgery. In order to increase the quality of blocks and reduce the amount of pain, many drugs are used with lidocaine. In this study, the effect of ketorolac-lidocaine in intravenous regional anesthesia was investigated. Methods: 40 patients undergoing elective upper limb with America Society of Ane...
[ 14 ] - Does the low-density lipoprotein cholesterol play a key role in predicting metabolic syndrome in the Iranian adult population?
Background: The low density lipoprotein cholestrol (LDL-C) has an important role in the pathogenesis of cardiovascular disease but its association and predictive accuracy with metabolic syndrome (MetS) remains controversial. The objective of this study was to investigate the association and predictive ability of LDL-C with MetS. Methods: We analyzed the data from a population-based cross-secti...
[ 15 ] - Diagnostic accuracy of fecal calprotectin in assessing the severity of inflammatory bowel disease: From laboratory to clinic
Background: Inflammatory bowel disease (IBD) involves chronic inflammation of the digestive tract. In the past decades, fecal calprotectin has been proposed as a useful biomarker for the differential diagnosis between IBD patients and healthy controls. We designed this study to evaluate the diagnostic ability of fecal calprotectin (FC) and conventional inflammatory markers in IBD patients. M...
[ 16 ] - The effect of green tea consumption on oxidative stress markers and cognitive function in patients with Alzheimer’s disease: A prospective intervention study
Background: Alzheimer’s disease (AD) is the most prevalent degenerative disorder of the brain among elderly individuals. Many studies indicate that oxidative stress is an important pathogenic factor which involves oxidizing macromolecules such as DNA, lipids, and proteins in AD. Green tea is a rich source of antioxidant compounds that can remove radical oxygen species. The purpose of this...
[ 17 ] - Gender differences in the health status of elderly living alone, compared to those who are not alone: Evidence of the AHAP study, North of Iran
Background: One of the factors that have impact on the health status of elderly people is living alone. This study was conducted to examine the living condition of elderly population in Babol and probable differences which this condition induced on the health disorders of elderly people. Methods: This cross-sectional study was performed on 1544 elderly people aged 60 and over in Amirkola, Ba...
[ 18 ] - Associated factors of diabetic retinopathy in patients that referred to teaching hospitals in Babol
Background: Information regarding the frequency and severity of eye involvement in diabetic patients and its risk factors can be useful for prevention and treatment. This study aimed to determine the prevalence of diabetic retinopathy and its associated risk factors in diabetic patients who referred to teaching hospitals in Babol, Mazandaran. Methods: In this study a total of 1562 patients...
[ 19 ] - Sex difference of biological variation of BMI and waist circumference with age in Iranian adults: A predictive regression model
Background: Background and Objectives: The biological variation of body mass index (BMI) and waist circumference (WC) with age may vary by gender. The objective of this study was to investigate the functional relationship of anthropometric measures with age and sex.Methods: The data were collected from a population-based cross-sectional study of 1800 men and 1800 women aged 20-70 years in...
[ 20 ] - Metabolic syndrome and the associated risk factors in Iranian adults: A systematic review
Background: Metabolic syndrome (MetS) is a complex clustering cardiovascular risk factors such as abdominal obesity, hypertension, diabetes and dyslipidemia. It has been a growing health problem in Iranian adults in recent decade. The objective of this article was to review the prevalence of MetS and the corresponding risk factors among Iranian adults.Methods: We conducted a systematic revi...
[ 21 ] - Immunohistochemical expression of CD10 in cutaneous basal and squamous cell carcinomas
Background: Non-melanoma skin cancer is the most common malignant tumor in humans. The role of ultraviolet radiation is well-known in the pathogenesis of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). CD10 is a zinc-dependent metallopeptidase known as common acute lymphoblastic leukemia antigen (CALLA). Although CD10 expression has been investigated in some cutaneous tu...
[ 22 ] - Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our ...
[ 23 ] - Association of Helicobacter pylori Infection With Colon Cancer and Adenomatous Polyps
Background and objective: Helicobacter pylori infection is one of the most common chronic bacterial infections in the world, especially in the developing countries. This bacterium is the cause of many diseases such as lymphoma, gastritis, peptic ulcers, and stomach cancer. According to recent reports, H. pylori infection can potentially increase the risk of colon cancer. The cu...
[ 24 ] - نقش پیشگویی کننده لکوسیتوز، آنمی و ترومبوسیتوز قبل از جراحی با شدت تومورهای اپیتلیالی تخمدان
سابقه و هدف: کانسر تخمدان ششمین سرطان شایع در بین زنان در جهان است. شمارش سلولهای خونی قبل از عمل میتوانند بیومارکرهای پیشگویی کننده شدت انواع سرطان و تعیین نوع عمل جراحی باشند. لذا این مطالعه به منظور بررسی نقش پیشگویی سه مارکر خونی آنمی، لکوسیتوز و ترومبوسیتوز با مرحله و درجه کانسرهای اپی تلیال تخمدان قبل از عمل جراحی پرداخته است. مواد و روشها: در این مطالعه مقطعی اطلاعات مربوط به ۶۰ بیما...
[ 25 ] - مقایسه اثرخواب آوری و مدت ریکاوری دکس مدتومدین و فنتانیل حین کلونوسکوپی الکتیو
سابقه و هدف: داروهای مختلفی از جمله پروپوفول یا میدازولام با یا بدون فنتانیل بعنوان آرام بخشبرای کلونوسکوپی بکار می روند.دکس مدتومدین یک داروی آرام بخش جدید می باشد که بافعال کردن رسپتورهای آلفا2 آدرنرژیک در مغز و طناب نخاعی اثرات سداتیو، ضددرد و سمپاتولیتیک دارد.این مطالعهبه منظور مقایسه اثر خواب آوری و مدت ریکاوری دکس مدتومدین و فنتانیل حین کلونوسکوپی الکتیو انجام شد. مواد وروشها: در این مطا...
[ 26 ] - الگوی تغییرات ده ساله سن ابتلا به انفارکتوس حاد میوکارد در بستری شدگان بیمارستان شهید بهشتی بابل (80-1371)
Background and Aim: Acute myocardial infarction (AMI) is one of the most common diseases with a high mortality rate, disability, and complications, in developing countries, because in the recent decade, coronary diseases have been the major cause of death in Iran. Thus, this study aimed at investigating a 10-year period of age variation in patients with acute myocardial infarction. Materials...
[ 27 ] - Comparison of pathologic characteristics of breast cancer in younger and older women
Background: Breast cancer is the most common invasive cancer with high mortality in women all around the world. The present evidence shows that younger patients have poor survival. Thus, the aim of this study was to compare the pathologic characteristics of breast cancer in women younger than 40 years compared with older. Methods: This is a cross-sectional study which contains 681 patients wit...
[ 28 ] - Comparison of bladder ultrasonographic and rigid cystoscopic findings in patients with hematuria
Background: Bladder cancer ranks ninth in world-wide cancer incidence and is 2.5-4 times more common in men, and painless gross hematuria is its typical clinical symptom. Cystoscopy is used to evaluate the cause of hematuria in bladder while the use and reliability of ultrasonography is questionable for this purpose. Therefore, the aim of this study was to compare abdominal ultrasonography and ...
[ 29 ] - Relationship of social capital with overweight and obesity among female health care workers
Background: The epidemic of obesity has turned into a major global health challenge. Environmental and social factors such as social capital, can significantly affect obesity. This study aimed to evaluate the relationship of social capital with overweight and obesity among female health-care workers. Methods: This cross-sectional study was conducted in 2018 on 680 female health-care workers wh...
[ 30 ] - Serum Irisin level in patients undergoing different Stages of Chronic Kidney Disease
Background: Irisin is a myokine that regulates energy metabolism by inducing browning of adipose tissue. The aim of this study was to evaluate the relationship between irisin level and biochemical parameters of chronic kidney disease (CKD) patients in stage 2 and stage 4. Methods: The research was a cross-sectional study; the study population included patients with CKD who were over 18 years o...
[ 31 ] - Effect of levothyroxine on cardiac function in children with subclinical hypothyroidism: A quasi-experimental study
Background: Because of the importance of thyroid function and its effect on different organs, such as the heart, this study was aimed to evaluate the effect of levothyroxine on cardiac function in children with subclinical hypothyroidism. Methods: This quasi-experimental study was performed on children aged 4-12 years old with diagnosis of subclinical hypothyroidism in Amirkola Children's Hosp...
[ 32 ] - Comparing the effect of kangaroo mother care and field massage on serum bilirubin level of term neonates with hyperbilirubinemia under phototherapy in the neonatal ward
Background: Several factors contribute to the effectiveness of phototherapy. The aim of this study was to compare the effect of kangaroo mother care (KMC) and field massage on bilirubin level of term neonates with hyperbilirubinemia under phototherapy in the neonatal ward. Methods: This double-blind clinical trial was performed on 90 term neonates aged 48 hours with hyperbilirubinemia, hospita...
[ 33 ] - Triglyceride to high-density lipoprotein cholesterol and low-density lipoprotein cholestrol to high-density lipoprotein cholesterol ratios are predictors of cardiovascular risk in Iranian adults: Evidence from a population-based cross-sectional study
Background: The superiority of TG/HDL-C and LDL-C/HDL-C ratios in predicting CVD risk is a matter of debates. Thus, the objective of this study was to compare TG/HDL-C and LDL-C to HDL-C ratios in predicting the risk of CVD events. Methods: In a population-based cross-sectional study, 567 representative participants aged 40 years or older were entered in the study in Babol, North of Iran. The...
[ 35 ] - Comparing the Outcomes of Minimal Incision and Double Incision in Treatment of Carpal Tunnel Syndrome: A Randomized Controlled Trial
Background and purpose: Carpal tunnel syndrome is the most prevalent neuropathy caused by trapping and median nerve compression in the wrist. This study aimed at comparing the effects of minimal incision and double incision in treatment of patients with carpal tunnel syndrome. Materials and methods: This randomized controlled trial was performed in 50 patients with carpal tunnel syndrome atten...
[ 36 ] - Delayed phases of contrast MRI, can it be valuable in multiple sclerosis active phase diagnosis?
Background: Observing the enhancing plaques in magnetic resonance imaging (MRI) is one of the most valuable diagnostic modalities in confirming the diagnosis of multiple sclerosis (MS), its recurrence and for better detection of active disease. Since active lesions discovery can improve designating diffusion in time diagnosis of MS and controlling disease activity, and there is not any definite...
[ 37 ] - Assessment of the Diagnostic Value of GFAP, IGFBP-2, and YKL-40 in Patients with Glioblastoma
Background and Aims: An effective marker search in glioblastoma is precious in controlling and detecting the progression and monitoring of patients with glioblastoma. In this regard, the present study aimed to evaluate the diagnostic and prognostic role of glial fibrillary acidic protein (GFAP), insulin-like growth factor-binding protein -2 (IGFBP-2), and chitinase-3-like protein -1 (YKL-40) ti...
[ 38 ] - Role of scaling combination of risk factors in clinical and imaging findings during pregnancy in predicting placenta accreta spectrum
Background: Placenta accreta is one of the known causes of maternal mortality and morbidity. If diagnosed before delivery, appropriate actions can be taken. The aim of this study was to investigate the role of scaling combination of risk factors in predicting placenta accreta spectrum (PAS). Methods: In this cross-sectional study, 120 pregnant women with two criteria and more of placenta previ...
[ 39 ] - Accuracy of obesity indices alone or in combination for prediction of diabetes: A novel risk score by linear combination of general and abdominal measures of obesity
Background: The predictive power of obesity measures varies according to the presence of coexistent measures. The present study aimed to determine the predictive power of combinations of obesity measures for diabetes by calculation of a linear risk score. Methods: Data from a population-based cross-sectional study of 994 representative samples of Iranian adults in Babol, Iran were analyzed. Me...
[ 40 ] - The Effects of Atorvastatin Consumption on Biochemical Variables in Patients with Type 2 Diabetes Mellitus and Pre-diabetes
Background and Aims: Atorvastatin may alter glycemic traits and lipid profiles. This study aimed to evaluate the effects of atorvastatin on biochemical variables in patients with type 2 diabetes and pre-diabetes (borderline diabetes). Materials and Methods: This study included 80 individuals divided into five groups. Patients with type 2 diabetes mellitus and pre-diabetes used atorvastatin 20...
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