Monireh Mohsenzadegan
Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Immunomodulation of TLR2 and TLR4 by G2013 (alfa-L-Guluronic acid) in CVID Patients
Background: Common variable immunodeficiency (CVID) is a primary immune disorder associated with hypogammaglobulinemia, recurrent infections and autoimmune diseases. CVID patients are frequently in contact with infectious pathogens leading to the activation of innate immunity through Toll-like receptors (TLR) affecting adaptive immunity. The aim of the present study was to test the immunomedula...
[ 2 ] - میکروRNAهای گردشی، بیومارکرهای ارزشمند در مایعات بیولوژیک بدن
MicroRNAs (miRNAs) are severely protected sequences and single stranded structures approximately 18 to 25 nucleotides in length. The crucial role of miRNAs has been previously proved in the regulation of the gene expression in post transcriptional modification events of messenger RNA. The precise mechanism by which miRNAs modulate translational repression of mRNAs is not fully determined. Howev...
[ 3 ] - Study of NGEP expression in androgen sensitive prostate cancer cells: A potential target for immunotherapy
Background: Prostate cancer is one of the leading causes of cancer deaths among men. New gene expressed in prostate (NGEP), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. Because of its selective expression in prostate cancer cell surface, NGEP is a potential immunotherapeutic target. To target the NGEP in prostate cancer, it is essential to investig...
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