Fereshteh Golab
Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
[ 1 ] - The Effects of Different Dose of Chronic Ritalin on the Brain of Prepubertal Female Balb/C Mice
Background Methylphenidate (MPH) is commonly prescribed for children who have been diagnosed with attention deficit hyperactivity disorder (ADHD); however, the action mechanisms of methylphenidate have not been fully elucidated. Studies have shown a relationship between apoptosis signaling pathways and psychiatric disorders, as well as therapeutic targets for such disorders. So, we examined the...
[ 2 ] - اثرات اکستازی بر سیستم عصبی
مقدمه: اکستازی یک داروی توهم‌زای قوی است که به طور گسترده به‌عنوان یک داروی خیابانی استفاده می‌شود. این دارو می‌تواند خلق و خو و ارتباطات اجتماعی را در کوتاه مدت بهبود ببخشد. مطالعات در انسان‌ها و حیوانات نشان داده است که اکستازی می‌تواند سبب اثرات سمّی بر روی سیستم عصبی شود. اگرچه تحقیقات بسیاری بر روی اکستازی انجام شده است اما مکانیسم عمل آن هنوز به طور کامل شناخته نشده است. اکستازی قادر است س...
[ 3 ] - The Mediating Role of A2A Adenosine Receptors in the Mitochondrial Pathway of Apoptotic Hippocampal Cell Death, Following the Administration of MDMA in Rat
Introduction: The 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is a popular recreational drug and a major source of substance abuse, which ultimately leads to sensations of well-being, elation and euphoria, moderate derealization/depersonalization, and cognitive disruptions, as well as intense sensory awareness. The mechanisms involved in memory impairment induced by MDMA are not completel...
[ 4 ] - اثر مداخله ورزش بر عوامل درگیر بر بیان ژن عوامل تحریکی و مهاری رگ‌زایی به دنبال ایسکمی ریپرفیوژن مجدد عضله قلب
مقدمه: فرایند رگ‌زایی برای موضع آسیب‌دیده در قلب امری حیاتی است. این مطالعه با هدف بررسی اثر مداخله ورزش بر عوامل درگیر بر بیان ژن عوامل تحریکی و مهاری رگ‌زایی به دنبال ایسکمی ریپرفیوژن مجدد عضله قلب صورت گرفته است. روش بررسی: در این مطالعه 28 رت صحرایی نر ویستار (250-200 گرم) به صورت تصادفی در 4 گروه شم، ایسکمی، تمرین و تمرین- ایسکمی مورد استفاده قرار گرفتند. آنفارکتوس میوکارد با بستن شریا...
[ 5 ] - Effect of 8-week resistance training on HIF-1α gene expression and Endothelial Progenitor Cells recall of blood after one session of resistance activity in elderly men
Abstract Background and Objectives Dysfunction of endothelial cells is associated with the development of atherosclerosis and cardiovascular disease. Adult endothelial progenitor cells are derived from hematopoietic stem cells capable of forming new blood vessels through a process of angiogenesis. This study was to investigate the effect of resistance training on HIF-1α gene expression and rec...
[ 6 ] - Dalteparin as a Novel Therapeutic Agent to Prevent Diabetic Encephalopathy by Targeting Oxidative Stress and Inflammation
Introduction: Hepcidin is the principal modulator of systemic iron metabolism, and its role in the brain has been clarified recently. Studies have shown hepcidin plays an important role for in neuronal iron load and inflammation. This is of significance because neuronal iron load and inflammation are pathophysiological processes that have been highly linked to neurodegeneration. Moreover, the a...
[ 7 ] - Response of Endothelial Progenitor Cells and Expression of Angiogenic Cytokine Genes in Preconditioning with Resistance Training in Elderly Men
Introduction: Impairment in the endothelial function starts with aging; however, it can be reduced or prevented by regular exercise. This study aimed to investigate the response and compatibility of endothelial progenitor cells and to evaluate the gene expression of hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) after eight weeks of resistance training in the e...
[ 8 ] - Assessing the Association Between Fennel (Foeniculum Vulgare) Extract and Serum Lipid Profile and Leptin Receptor Expression
Introduction:Obesity is one of the most serious challenges of our era, with significant health consequences and high economic burden for health systems. Therefore, many countries have developed political agendas to cope with this ever-rising challenge. Along with chemical medications that are developed to manage obesity, researchers have focused on some natural ingredients and herbal extracts w...
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