The Effectiveness of Aerobic Training with Supplementation of Vitamins C and E on Some Inflammatory and Cardiovascular Risk Factors of Overweight Men

The purpose of this study was to investigate the effectiveness of aerobic training with supplementation of vitamins C and E on some inflammatory markers and cardiovascular risk factors for overweight men. In this semi-experimental study, 30 overweight men were randomly assigned into three groups (n=10, AT+Sup, AT+Placebo, and control). The exercise program consisted of three sessions per week with intensity 60-75% of maximal heart rate for six weeks. The daily supplement group received a dose of 300 mg of vitamin E and a 400 mg tablet of vitamin C and a placebo group daily for one gelatin capsule during this period. Before and after six weeks intervention were measured IL-6, CRP, TG, LDL, HDL and insulin resistance index. Data were analyzed by t-test, one way ANOVA and Tukey post hoc test at a significant level of P<0.05. The results showed that aerobic training significantly reduced the body fat percentage, TG and LDL in both supplement and placebo groups (P<0.05). However, this reduction was observed in IL-6 and CRP only in the supplement group (P<0.05). On the other hand, the results showed that exercise and supplementation did not change the insulin resistance of subjects. The results of analysis of variance showed that there was a significant difference between the three groups in fat percentage, IL-6, CRP, TG and LDL (P<0.05). According to the results of this research, probably six weeks of aerobic training plus supplements with vitamin E and C may help to reduce inflammatory symptoms, body fat percentage and some cardiovascular risk factors.