The Effect of Aerobic Exercise on Hepatic Factors in Antidote Production Horses

Background & aim: Iran is one of the most exclusive antidote producers within the middle east. Therapeutic serum production of high quality treatment and fewer side effects have  significant impact on public health of the community. this may only be attainable if eutherian and animal health are to be provided. The use of sports activities as a nonpharmacological method will play a crucial role in maintaining and improving the health of the livestock. The purpose of this study was to investigate the result of aerobic exercises on hepatic factors (AST,ALT,GGT) in antidote production horses.   Methods:Sixteen horses  were randomly divided into two groups of venom and venom + training  group for 22 weeks within the antidote production cycle. The exercise protocol consisted of three sessions of aerobic exercise per week, with moderate intensity. Blood samples at three totally different times: Before the beginning of the protocol, end of the 11-week period and therefore the end of the 22-week period were collected through the jugular vein and evaluated by repeated measures of variance analysis.   Results: Data analysis showed that 22 week aerobic exercise training in venom + training  group reduces the activity of the ALP and GGT enzyme (p=0/03) and the results showed a significant decrease in AST (p=0/02) and ALT (p=0/001) enzyme activity as a result of training compared to the control group.   Conclusion: Aerobic training seems to be effective in reducing the effects of venom by reducing the levels of liver enzymatic activity in antidote producing horses