Synthesis of 2-Amino-3,5-dicarbonitrile-6-thiopyridines Using Silica-bonded N-Propyldiethylenetriamine as a Heterogeneous Solid Base Catalyst

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چکیده مقاله:

Silica-bonded N-propyldiethylenetriamine (7) is employed as a recyclable heterogeneous solid base catalyst for the synthesis of 2-amino-3,5-dicarbonitrile-6-thiopyridines through pseudo four-component condensation reaction between aromatic aldehydes, malononitrile, and 2-amino-thiophenol in refluxing ethanol. Silica-bonded N-propyldiethylenetriamine showed much the same efficiency when used in consecutive reaction runs.

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synthesis of 2-amino-3,5-dicarbonitrile-6-thiopyridines using silica-bonded n-propyldiethylenetriamine as a heterogeneous solid base catalyst

silica-bonded n-propyldiethylenetriamine (7) is employed as a recyclable heterogeneous solid base catalyst for the synthesis of 2-amino-3,5-dicarbonitrile-6-thiopyridines through pseudo four-component condensation reaction between aromatic aldehydes, malononitrile, and 2-amino-thiophenol in refluxing ethanol. silica-bonded n-propyldiethylenetriamine showed much the same efficiency when used in ...

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عنوان ژورنال

دوره 3  شماره 1

صفحات  16- 24

تاریخ انتشار 2017-03-01

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