Solubility of Naproxen in Polyethylene Glycol 200 + Water Mixtures at Various Temperatures
نویسندگان
چکیده مقاله:
The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree model with van’t Hoff equation can be used to predict solubility in PEG 200 + water with only four solubility data in mono-solvents. Theobtained solubility calculation errors vary from ~ 17 % up to 35 % depend on the number of required input data.Non-linear enthalpy-entropy compensation was found for naproxen in the investigated solvent system and the Jouyban−Acree model provides reasonably accurate mathematical descriptions of the thermodynamic data of naproxen in the investigated binary solvent systems.
منابع مشابه
solubility of naproxen in polyethylene glycol 200 and water mixtures at various temperatures
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solubility of naproxen in polyethylene glycol 200 + water mixtures at various temperatures
the solubility of naproxen in binary mixtures of polyethylene glycol 200 (peg 200) + water at the temperature range from 298.0 k to 318.0 k were reported. the combinations of jouyban-acree model + van’t hoff and jouyban-acree model + partial solubility parameters were used to predict the solubility of naproxen in peg 200 + water mixtures at different temperatures. combination of jouyban-acree m...
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عنوان ژورنال
دوره 14 شماره 4
صفحات 1041- 1050
تاریخ انتشار 2015-10-01
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