Prediction of Refractive Outcome of Second Eye with Partial Adjustment of Intraocular Lens Power of the First Eye

Background and Objective: This study aimed at comparing the results of refractive cataract surgery in patients undergoing sequential surgeries in both eyes. Considering the preoperative refraction and final refraction of the first eye, it is possible to correct the refrative result of cataract surgery using the adjustment of the second eye intraocular lens (IOL) power. Materials and Methods: This study was conducted based on a matched-pair clinical-trial design. Regarding the final result of the first eye refraction,  the adjustment of the second eye IOL power was determined by 50% of uncorrected refractive error. Finally, the mean spherical equivalent (SE) of the first and second eyes were determined, and the differences were analyzed using a paired t-test at a significant level of 95%. Results: A total of 470 candidates who underwent bilateral sequential cataract surgery were investigated in this study.  The refractive errors ranged from -8.25 to + 6.50 and from -6.75 to +7.25 for the first and second eyes, respectively. The mean values of SE for the first and second eyes were 2.55 and 2.48 preoperatively, and 1.13 and 0.47 postoperatively, respectively. Moreover, there was a significant difference between the two groups (P<0.001).  Conclusion: The adjustment of IOL power for the second eye by 50% of uncorrected refractive error of the first eye led to acceptable outcomes.