Patients with Down syndrome in the coronavirus Pandemic (Covid 19)

Background and purpose: Coronavirus (QUID-19) is an infectious disease of the respiratory system that has been identified by the World Health Organization as an epidemic. Patients with Down syndrome are more likely to develop Quidd-19 disease with more severe complications due to the underlying comorbidities they have. The aim of this study was to evaluate the complications of Covid-19 disease in patients with Down syndrome. Materials and Methods: This descriptive-prospective and applied study was performed in 1400 on 111 patients with Covid 19 with an age range of 20-40 years referred to hospitals in southwestern Iran, whose disease was confirmed by CT scan and RT-PCR. Is done. 15 patients with Down syndrome and 96 patients were considered as a control group. SPSS ver19 software was used for statistical analysis. Results: In this study, 15 patients with Down syndrome with infection of Covid 19 virus (mean age 26.14 ±11 years) and 96 patients with Covid 19 virus as control group (mean age 38.34 ± 23.2 years) were studied. In the group with Down syndrome, there were 9 males and 6 females, and in the control group, 54 males and 42 females. Further studies to determine the condition of patients revealed that in patients with Down syndrome, the rate and percentage of hospitalizations in the intensive care unit were 8 (53), intubation 7 (45), hospital discharge 7 (45) and mortality 8 (54). In the control group, the rate and percentage of hospitalizations in the intensive care unit were 4 (4), intubation was 4 (4), hospital discharge was 92 (92) and mortality was 4 (4)(p<0.05( Conclusion: The results of this study showed that due to immune system disorders and physical and clinical aspects of people with Down syndrome, there is a concern that these patients are more at risk of death from coronavirus than other people in the community. Therefore, more care and supervision by their caregivers to prevent infection with the Covid-19 virus, adequate care by the treatment staff in hospitals in case of hospitalization, and placing these people in the priority of receiving vaccination. It can also help raise awareness of infectious diseases and pandemics that may occur in the future.