P-239: Effect of Grass Kebar (Biophytum Petersianum Klotszch) to Increase Uterus Fertility and Increasing Number of Children on Female White Rat (Rattus norvegicus)

Background: Grass Kebar (Biopytum petersianum Klotzch) is one of Indonesian medicinal plants, which can only be found in Kebar sub-district, Manokwari, Irian Jaya. This plant is mainly used by the community Manokwari to maintain the fertility of women of reproductive organs. This study aims to determine the effect of extract Grass Kebar dose on the fertility of the uterus and the number of progeny of white rats (Rattus norvegicus) are produced. Materials and Methods: To determine the effect of plant extracts against the fertility of the uterus, performed Completely Randomized Design with six replications. Female rats fed grass Kebar orally at doses of 0.51 ml, 1.02 ml, 1.53 ml and without grass Chebar (control). Effects of extracts of the progeny is done through the provision of Grass Kebar in female rats at doses of 0.51 g / ml, 1.21 g / ml, 1.53 g / ml, 2.04 g / ml and 2.55 g / ml with simple random sampling. Results: The results showed that the increase in endometrial thickening is proportional to the dose given Kebar grass, with the optimal dose of 1.51 ml. Provision of grass Kebar also showed a significant effect on increasing the number of white female pups. Effective dose Kebar grass in increasing the number of children of white rats (Rattus norvegicus) female was 2.04 g / ml. Conclusion: Kebar grass proved to affect the fertility of the reproductive organs are indicated by the thickening of the endometrium and an increase in the number of children female rats.